青岛大学医学院学报2017，Vol.53Issue(1)：52-55,4.DOI:10.13361/j.qdyxy.201701016
妊娠早期妇女维生素D营养状态及其与甲状腺功能减退症关系
CORRELATION BETWEEN VITAMIN D NUTRITIONAL STATUS AND HYPOTHYROIDISM IN EARLY PREGNANCY
刘鑫颖 1彭伟 2王丽霞 3申宝明 4赵文娟1
作者信息
- 1. 青岛大学附属医院内分泌科,山东青岛 266003
- 2. 青岛大学附属医院产科
- 3. 淄博市临淄区人民医院内分泌科
- 4. 青岛大学附属医院信息管理部
- 折叠
摘要
Abstract
Objective To investigate the serum level of 25(OH) D in early pregnancy women and its correlation with hypothyroidism.Methods A detection of serum 25 (OH) D,thyrotropin (TSH),free thyroxine (FT4),free triiodothyronine (FT3),and thyroid peroxidase antibody (TPOAb) was conducted in 248 cases of early pregnancy.Results The level of serum 25(OH) D in early pregnancy women was 5.35-44.33 μg/L,the median being 13.14 μg/L.The constituent ratios of each group with vitamin D deficiency,lack of vitamin D,and vitamin D sufficiency were 88.71％ (220/248),8.87％ (22/248) and 2.42％ (6/248),respectively.The differences in prevalence of hypothyroidism among serum levels of TSH,FT4 and FT3 in vitamin D nutritional status were not significant (P＞0.05).There were no significant differences between hypothyroidism groups and normal thyroid function group in terms of 25(OH) D and frequency distribution (P＞0.05).The level of serum 25(OH) D was not correlated with TSH,FT4,FT3,and TPOAb (P＞0.05).The serum level of 25(OH) D in sunny season group was higher than that in lack of sunshine season group (Z=-10.54,P＜0.05).Conclusion Deficiency of 25(OH) D is common in early pregnancy women,and season has a certain influence on its level.关键词
妊娠初期/维生素D/甲状腺功能减退症/促甲状腺素Key words
pregnancy trimester, first/vitamin D/hypothyroidism/thyrotropin peroxidase分类
医药卫生引用本文复制引用
刘鑫颖,彭伟,王丽霞,申宝明,赵文娟..妊娠早期妇女维生素D营养状态及其与甲状腺功能减退症关系[J].青岛大学医学院学报,2017,53(1):52-55,4.
