日用化学工业（中英文）2017，Vol.47Issue(4)：207-211,5.DOI:10.13218/j.cnki.csdc.2017.04.006
冰川水和五脉绿绒蒿提取物的美容功效研究
Study on cosmetological efficacy of glacier water and Meconopsis quintuplinervia extract
陈迪 1章漳 2蒋耀权 2方兆华 2丛峰松1
作者信息
- 1. 上海交通大学生命科学技术学院,上海 200240
- 2. 伽蓝(集团)股份有限公司,上海 200040
- 折叠
摘要
Abstract
The effect of glacier water and Meconopsis quintuplinervia extract on human dermal fibroblast-adult (HDF-a)was studied respectively and collaboratively. Effect of glacier water and Meconopsis quintuplinervia extract on cell proliferation activity of HDF -a was evaluated by MTT assay and on level of cellular ATP (adenosine triphosphate)with an ATP Assay Kit. Effect of glacier water and Meconopsis quintuplinervia extract on content of hyaluronic acid in extracellular matrix (ECM )of HDF-a was evaluated by Enzyme-linked immunosorbent assay (ELISA)and their effect on expression of collagenⅠand elastin in ECM was detected by Western Blot. The results show that,as comparing with the control group,glacier water can promote the proliferation activity and energy metabolism level of HDF-a as well as enhancing cellular content of hyaluronic acid compared with the control group. Glacier water also displays a capacity of enhancing the expression of elastin. All of the above - mentioned differences are statistically significant. The effect of Meconopsis quintuplinervia extract with respect to the above-mentioned aspects is more obvious than that of glacier water, and the extract shows an ability of promoting the expression of collagenⅠ. When glacier water and Meconopsis quintuplinervia extract are used collaboratively,their efficacy on HDF-a is much more obvious.关键词
化妆品添加剂/冰川水/五脉绿绒蒿提取物/人真皮成纤维细胞/抗衰老/保湿Key words
cosmetic additive/glacier water/Meconopsis quintuplinervia extract/HDF - a/anti - sanility/moisturizing分类
化学化工引用本文复制引用
陈迪,章漳,蒋耀权,方兆华,丛峰松..冰川水和五脉绿绒蒿提取物的美容功效研究[J].日用化学工业（中英文）,2017,47(4):207-211,5.
