四川医学2017，Vol.38Issue(4)：373-375,3.DOI:10.16252/j.cnki.issn1004-0501-2017.04.004
血清脂蛋白相关磷脂酶A2与急性冠脉综合征危险分层的相关性研究
Correlation Study of Serum Lipoprotein Associated Phospholipase A2 and Risk Stratification of Acute Coronary Syndrome
摘要
Abstract
Objective To investigate the correlation between serum lipoprotein associated phospholipase A2(Lp-PLA2)and GRACE scoring,risk stratification of acute coronary syndrome(ACS).Methods 203 cases of confirmed ACS patients hospitalized between November 2012 and June 2016 in our department were included and divided into low-risk group(83 cases),medium-risk group(31 cases)and high-risk group(124 cases)according to GRACE scoring.Serum Lp-PLA2 level was determined and relationship between serum Lp-PLA2 level and GRACE scoring was analyzed.Results Serum Lp-PLA2 level in low-risk group was(171.31 ± 58.31)ng/mL,in medium-risk group was(258.42±78.94)ng/mL and in high-risk group was(309.84 ± 91.73)ng/mL.Comparing the Lp-PLA2 level of the three groups,there were statistically significant differencesamong the three groups(P<0.05).Linear regression analysis indicated a positive correlation between serum Lp-PLA2 level and GRACE scoring in ACS patients(r=0.791,P<0.01).Conclusion Serum Lp-PLA2 level has certain clinical significance for the early evaluation of risk degree of ACS patients.关键词
急性冠脉综合征/危险分层/全球急性冠状动脉事件注册评分/脂蛋白相关磷脂酶A2Key words
acute coronary syndrome/risk stratification/global acute coronary events registry score/lipoprotein associated phospholipase A2分类
医药卫生引用本文复制引用
艾民,颜昌福,夏福纯,周双陆,贺剑,李翠萍..血清脂蛋白相关磷脂酶A2与急性冠脉综合征危险分层的相关性研究[J].四川医学,2017,38(4):373-375,3.基金项目
四川省卫生和计划生育委员会科研课题(编号:150097) （编号:150097）
