摘要
Abstract
Objective To investigate the effects of ropivacaine combined with sufentanil for epidural analgesia on delivery outcome and maternal stress response.Methods 100 pregnant women were randomly divided into observation group and control group (n=50).The observation group was treated with labor analgesia,while the control group was given natural childbirth.Maternal pain,labor time,neonatal Apgar score and levels of serum malondialdehyde (MDA),activity of superoxide dismutase (SOD) of two groups were compared.Results Before analgesia,the VAS scores of the two groups were similar,and the difference was not statistically significant (P>0.05).The VAS score of the observation group was significantly lower than that of the control group at 10 min,30 min andthe total opening of the cervix after analgesia,and the difference was statistically significant (P<0.05).The maternal active period and the second labor time of observation group were both shorter than those in control group,the difference was statistically significant (P<0.05).The third labor time of the observation group was similar to that of the control group,the difference was not statistically significant (P>0.05).1 min,5 min,and 10 minafter birth,the Apgar score of the two groups of neonates were similar,and the difference was not statistically significant (P>0.05).The natural childbirth rate of the observation group was increased,and the rate of cesarean section was lower.Compared with the control group,the difference was statistically significant (P<0.05).Before analgesia,maternal blood SOD activity and MDA levels of the two groups were similar,and the difference was not statistically significant (P>0.05).After delivery,the blood SOD activity of the two groups was higher than that before analgesia,the level of MDA was lower than that before analgesia,but the observation group improved more significantly,the difference was statistically significant (P<0.05).Conclusion Ropivacaine combined with sufentanil for epidural analgesia helps to reduce maternal pain,relieve stress,promote fetal childbirth,with no adverse effects on maternal and neonatal,and has high safety.关键词
罗哌卡因/舒芬太尼/镇痛分娩/分娩结局/应激反应Key words
ropivacaine/sufentanil/analgesia/delivery outcome/stress response分类
医药卫生
