天然产物研究与开发2017，Vol.29Issue(3)：489-496,8.DOI:10.16333/j.1001-6880.2017.3.023
Box-Behnken设计-效应面法优化离子液体提取废次茶叶中咖啡因工艺
Optimization of Ionic Liquids Extraction of Caffeine from the Discarding Tea by Box-Behnken Design and Response Surface Analysis
摘要
Abstract
With extraction yield of caffeine as evaluation index,the effects of liquid-solid ratio,extraction temperature,extraction time,concentration of ionic liquids [HSO3-pmim] + [HSO4]-were investigated through Box-Behnken design and response surface methodology based on single factor experiment.The results suggested that the optimal conditions of extraction technology were as follows:liquid-solid ratio was 0.05 g/mL,extraction time was 160 min,extraction temperature was 90 ℃,ionic liquids [HSO3-pmim] + [HSO4]-concentration was 70％.Under these conditions the extraction yield of caffeine was 95.1 mg/5g tea sample.The optimized extraction technology was reasonable,simple,precise and with good predictability.关键词
Box-Behnken设计-效应面法/离子液体[HSO3-pmim]+[HSO4]-/废次茶叶/咖啡因Key words
Box-Behnken design and response surface methodology/ionic liquids[HSO3-pmim] + [HSO4]-/discarding tea/caffeine分类
化学化工引用本文复制引用
黄飞,徐慧敏,王杰,黄涛,黄成相,吴孔林..Box-Behnken设计-效应面法优化离子液体提取废次茶叶中咖啡因工艺[J].天然产物研究与开发,2017,29(3):489-496,8.基金项目
安徽省大学生创新创业训练计划(201610375059,201510375017) （201610375059,201510375017）
安徽省高校自然科学研究一般项目(KJHS2016B06) （KJHS2016B06）
