天然产物研究与开发2017，Vol.29Issue(3)：503-510,8.DOI:10.16333/j.1001-6880.2017.3.025
天然(口山)酮类化合物生物活性的研究进展
Review on Pharmacological Activities of Natural Xanthone
摘要
Abstract
Xanthone is a collective name for one kind of natural plant secondary metabolites which possess tricyclic aromatic structure and widely distributed in the plants of several family such as Gentianaceae,Guttiferae,Polygalaceae,Moraceae and Leguminosae.The present studies showed that natural xanthones have wide range of pharmacological activities,including anti-tumor,anti-bacterial,anti-viral,hepatoprotective,pypoglycemic,inhibition of xanthine oxidase,etc.The review on pharmacological activities and related molecular mechanisms,structure-activity relationships of titled constituents over the last decade were summarized in this article,by which the prospect of development and utilization of natural xanthones can be prospected.The article provided the reference for the further research and comprehensive utilization of the natural xanthone resources.关键词
天然(口山)酮/药理作用/分子机制/构效关系Key words
natural xanthone/pharmacological activity/molecular mechanisms/structure-activity relationships分类
生物科学引用本文复制引用
樊冬梅,刘越,唐丽..天然(口山)酮类化合物生物活性的研究进展[J].天然产物研究与开发,2017,29(3):503-510,8.基金项目
国家自然科学基金(81274158、81373765) （81274158、81373765）
教育部新世纪优秀人才支持计划(NCET-12-0578、13-0624) （NCET-12-0578、13-0624）
国家民委科研项目(12ZYZ019) （12ZYZ019）
高等学校学科创新引智计划(B08044) （B08044）
