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先验图像约束的4D显微CT图像重建方法

沈涛 孙翌 吴华珍 陈功 罗守华

中国医疗设备2017,Vol.32Issue(5):54-59,6.
中国医疗设备2017,Vol.32Issue(5):54-59,6.DOI:10.3969/j.issn.1674-1633.2017.05.014

先验图像约束的4D显微CT图像重建方法

Prior Image Constraint Reconstruction Method in 4D Micro-CT

沈涛 1孙翌 1吴华珍 1陈功 2罗守华1

作者信息

  • 1. 东南大学 生物科学与医学工程学院,江苏 南京 210000
  • 2. 南京中医药大学附属医院 医学工程科,江苏 南京 210029
  • 折叠

摘要

Abstract

4D micro-CT imaging is a novelty and efficient method in disease surveillance and provides a living dynamic imaging information. Traditional cardio-respiratory gating strategies and micro-CT reconstruction methods have the disadvantages of long scanning time, high radiation dose, and motion artifact in reconstruction image. In order to solve those problems of traditional methods, this paper proposes a new 4D CT scanning and reconstruction method based on the gating technique and the prior image constraint compressed sensing (PICCS) reconstruction algorithm. This method utilizes the retrospective gating technique which demands continuous scanning of multiple rotations, the reconstruction result of respiratory phase sorted projections is set as the prior image in the PICCS reconstruction. The experimental results demonstrate that the proposed method can effectively obtain 4D reconstruction images with no streaking artifacts. 4D micro-CT imaging using PICCS provides image quality superior to FDK and OSART algorithms in both MSE and Peak Signal to noise ratio (PSNR) calculations. This method can provide fast acquisition and better images over existing methods.

关键词

4DCT/小动物成像/心脏成像/门控技术/先验图像

Key words

4D CT/small animal imaging/cardiac imaging/gating technique/prior image

分类

信息技术与安全科学

引用本文复制引用

沈涛,孙翌,吴华珍,陈功,罗守华..先验图像约束的4D显微CT图像重建方法[J].中国医疗设备,2017,32(5):54-59,6.

基金项目

国家自然科学基金面上项目"基于场发射电子源的快速X射线成像技术的研究"(61571124). (61571124)

中国医疗设备

OACSTPCD

1674-1633

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