医药导报2017，Vol.36Issue(5)：489-492,4.DOI:10.3870/j.issn.1004-0781.2017.05.007
草本威灵仙的抗炎镇痛和止血作用
Anti-inflammation, Analgesic and Hemostatic Effects of Veronicastrum sibiricum
王志江 1梁丽丽 1接明军 2魏国栋1
作者信息
- 1. 山东中医药高等专科学校, 烟台 264100
- 2. 山东省莱阳卫生学校, 烟台 264100
- 折叠
摘要
Abstract
Objective To explore the anti-inflammation, pain-relieving and bleeding-stopping effects of Veronicastrum sibiricum and its potential to be a medicinal resource of Radix clematidis.Methods Total of 120 mice were randomly divided into 6 groups, including the Veronicastrum sibiricum water extract (1.5, 1.0, 0.5 g·mL-1) groups, Radix clematidis water extract (1.0 g·mL-1) group, the 0.9% sodium chloride solution group and 2% aspirin solution group.The mouse hot-plate test and writhing test were carried out to evaluate the analgesic effect.The anti-inflammation effect was observed by the xylene-attracted swelling of the mouse's ears.The bleeding time of the breaking mouse's tails was used for studying hemostatic effect.Results The Veronicastrum sibiricum could significantly increase the pain threshold of mice in hot plate.At the same dosage, the Veronicastrum sibiricum reducing the writhing times of mice was similar to Radix clematidis.Auricle swelling inhibition rate was 5.72% higher than Radix clematidis (P<0.05);The mouse tail bleeding time was 7.6% shorter than Radix clematidis (P<0.05).Conclusion The Veronicastrum sibiricum shows similar analgesic effect to Radix clematidis,and more strong hemostatic and anti-inflammation effects than Radix clematidis.关键词
草本威灵仙/威灵仙/抗炎作用/镇痛作用/止血作用Key words
Veronicastrum sibiricum/Radix clematidis/Anti-inflammation effect/Analgesic effect/Hemostatic effect分类
医药卫生引用本文复制引用
王志江,梁丽丽,接明军,魏国栋..草本威灵仙的抗炎镇痛和止血作用[J].医药导报,2017,36(5):489-492,4.
