中国动脉硬化杂志2017，Vol.25Issue(4)：369-372,4.
低骨密度与非糖尿病性冠心病患者冠状动脉病变的相关性
Correlation between low bone mineral density and severity of coronary artery lesion in patients with non-diabetic coronary heart disease
摘要
Abstract
Aim To investigate the association between low bone mineral density (BMD) and severity of coronary artery lesion patients with non-diabetic coronary heart disease.Methods A total of 156 patients with non-diabetic coronary heart disease (CHD) with chest pain were enrolled in the study,clinical characteristic of patients was recorded,coronary artery lesion was determined by coronary angiography,the patients were grouped according to the number of coronary artery lesions:non-coronary artery lesion group,single coronary artery lesion group,double coronary artery lesion group,three coronary artery lesion group.Coronary artery clacification (CAC) was evaluated by 64 slice spiral CT,patients were grouped according to coronary artery calcification score:no calcification group (＜10 score),mild calcification group (10～ 100 score),moderate calcification group (101～400 score),severe calcification group (＞400 score).In addition,the bone mineral density (BMD) was measured by dual energy X-ray absorptiometry (DXA),according to the results,patients were divided into osteoporosis group,osteopenia group and normal bone group,and the difference of the degree of coronary artery lesions between the three groups was compared.Results With the severity of coronary artery calcification and coronary stenosis,the incidence of BMD were increased.The severity of coronary artery calcification and coronary stenosis in osteopenia group and osteoporosis group were significantly higher than that in normal group,there were statistically significant differences among the three groups (P＜0.01).Conclusion Low bone mineral density can be considered as an independent factor of coronary artery calcification and coronary stenosis in coronary heart disease patient without diabetes.关键词
低骨密度/冠心病/冠状动脉病变/冠状动脉钙化Key words
Low bone mineral density/Coronary heart disease/Coronary artery lesion/Coronary artery calcification分类
医药卫生引用本文复制引用
任晓妹,魏芹,邹继红,任利群,李荥娟,施伟,赵振,刘乃丰..低骨密度与非糖尿病性冠心病患者冠状动脉病变的相关性[J].中国动脉硬化杂志,2017,25(4):369-372,4.基金项目
国家自然科学基金项目(81170254、81300227) （81170254、81300227）
