中国感染控制杂志2017，Vol.16Issue(3)：203-206,4.DOI:10.3969/j.issn.1671-9638.2017.03.003
多重耐药菌感染性胰腺坏死的预后及其相关因素
Prognosis and related factors of infectious pancreatic necrosis caused by multidrug-resistant organisms
摘要
Abstract
Objective To investigate prognosis and related factors of infectious pancreatic necrosis(IPN) caused by multidrug-resistant organisms(MDROs).Methods Clinical data of 53 IPN patients admitted to a hospital between October 2010 and March 2016 were analyzed retrospectively,patients were divided into MDRO infection group and common bacterial infection group according to antimicrobial resistance of pathogens isolated from peripancreatic drainge fluid,prognosis and related factors of two groups were compared.Results Among 53 IPN patients with confirmed evidence for pathogenicity,33(62.3％)were in MDRO infection group,and 20(37.7％)were in common bacterial infection group,the most common MDROs isolated from peripancreatic drainage was multidrug-resistant Acinetobacter baumannii (MDRO-AB) (37.5％,18/48).The mortality of IPN patients was 30.2％ (16/53),mortality of MDRO infection group was higher than common bacterial infection group(39.4％ [13/33] vs 15.0％ [3/ 20],P＜0.05);the severity score,length of intensive care unit (ICU) stay,and hospitalization expenses in MDRO infection group were all higher than common bacterial infection group(all P＜0.05).The mortality of IPN patients were closely associated with MDRO infection and severity score of acute pancreatitis (all P ＜ 0.05).Conclusion Prognosis of patients with MDRO infection is poor,treatment is difficult,MDRO infection has become one of the most important challenge to the treatment of severe acute pancreatitis.关键词
重症胰腺炎/感染性胰腺坏死/多重耐药菌/多重耐药菌感染/预后Key words
severe pancreatitis/infectious pancreatic necrosis/multidrug resistance organism/multidrug resistance organism infection/prognosis分类
医药卫生引用本文复制引用
申鼎成,黄耿文,邹文茂,亢浩,周书毅..多重耐药菌感染性胰腺坏死的预后及其相关因素[J].中国感染控制杂志,2017,16(3):203-206,4.基金项目
中南大学湘雅医院医院管理研究基金项目(2016GL12) （2016GL12）
