摘要
Abstract
Objectives To study the fluctuation of serum uric acid in patients with hypertension complicated with different diseases.Methods From Mar.2014 to Jun.2015,a total of 100 patients with primary hypertension in our hospital were taken as the clinical research objects,and they were divided into A group (patients with simple hypertension),B group (patients with hypertension and coronary heart disease),C group(patients with hypertension and diabetes)and D group(patients with hypertension,coronary heart disease and diabetes).The serum uric acid (SUA) and mean arterial pressure (MAP) levels in the four groups were compared.Then,the four groups were regrouped into A+B+C group and D group,the SUA levels of the two groups were compared,and the SUA levels of hypertension and coronary heart disease group(A+B)and hypertension and diabetes group(C+D)were also compared.Results The concentration of UA in the four groups were A>B>C>D,the MAP levels in the four groups were A>D>C>B,and their differences were statistically significant(P<0.05);the SUA level in the A+B+C group was 324.15±4.87μmol/L which was obviously higher than that in the D group(P<0.05),the SUA level in the C+D group was 333.12±1.54μmol/L which was obviously higher than that in the A+B group(P<0.05),there was no significant difference in MAP after regrouping(P>0.05);and correlation analysis showed that SUA was positively correlated with MAP(r=+0.789,P<0.05).Conclusion The SUA level in patients with primary hypertension is highest;and the more complicated diseases,the lower uric acid level;and blood glucose may be an important factor affecting the SUA level in patients with hypertension and diabetes.关键词
高血压/并发/疾病/血尿酸/波动/差异Key words
Hypertension/Complicate/Disease/Serum uric acid/Fluctuation/Difference
