中国全科医学2017,Vol.20Issue(11):1300-1304,5.DOI:10.3969/j.issn.1007-9572.2017.01.y07
睡眠障碍与糖尿病的关系及其对糖代谢的影响研究进展
Research Progress of Relationship between Sleep Disorder and Diabetes and Its Effect on Glucose Metabolism
摘要
Abstract
Effects of sleep disorder on the glucose metabolism have increasingly aroused people's concern.Studies have shown that sleep disorder,especially sleep time shortening,is closely related to glucose metabolism,and has significant influence on insulin sensitivity.The abnormal glucose metabolism caused by sleep disorder maybe the important targets of future diabetes prevention and treatment.The paper reviews the relationship between sleep disorder and diabetes,effect of sleep disorder on levels of blood glucose and insulin resistance,and analyzes the changes of hypothalamic activity induced by sleep disorder,and the relations of hypothalamic-pituitary-adrenal axis,hypothalamic-pituitary-thyroid axis abnormities and glucose metabolism.It is concluded that the changes of neuroendocrine activity caused by sleep disorder are the potential mechanism of glucose metabolism,which provides a new direction for the prevention and treatment of these diabetic patients,and has important clinical significance.关键词
睡眠障碍/糖尿病/葡萄糖代谢障碍/综述Key words
Sleep disorders/Diabetes mellitus/Glucose metabolism disorders/Review分类
医药卫生引用本文复制引用
李佳琦,严悦蓉,余叶蓉..睡眠障碍与糖尿病的关系及其对糖代谢的影响研究进展[J].中国全科医学,2017,20(11):1300-1304,5.基金项目
国家自然科学基金资助项目(81600603) (81600603)