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睡眠障碍与糖尿病的关系及其对糖代谢的影响研究进展

李佳琦 严悦蓉 余叶蓉

中国全科医学2017,Vol.20Issue(11):1300-1304,5.
中国全科医学2017,Vol.20Issue(11):1300-1304,5.DOI:10.3969/j.issn.1007-9572.2017.01.y07

睡眠障碍与糖尿病的关系及其对糖代谢的影响研究进展

Research Progress of Relationship between Sleep Disorder and Diabetes and Its Effect on Glucose Metabolism

李佳琦 1严悦蓉 1余叶蓉1

作者信息

  • 1. 610041四川省成都市,四川大学华西医院内分泌代谢科
  • 折叠

摘要

Abstract

Effects of sleep disorder on the glucose metabolism have increasingly aroused people's concern.Studies have shown that sleep disorder,especially sleep time shortening,is closely related to glucose metabolism,and has significant influence on insulin sensitivity.The abnormal glucose metabolism caused by sleep disorder maybe the important targets of future diabetes prevention and treatment.The paper reviews the relationship between sleep disorder and diabetes,effect of sleep disorder on levels of blood glucose and insulin resistance,and analyzes the changes of hypothalamic activity induced by sleep disorder,and the relations of hypothalamic-pituitary-adrenal axis,hypothalamic-pituitary-thyroid axis abnormities and glucose metabolism.It is concluded that the changes of neuroendocrine activity caused by sleep disorder are the potential mechanism of glucose metabolism,which provides a new direction for the prevention and treatment of these diabetic patients,and has important clinical significance.

关键词

睡眠障碍/糖尿病/葡萄糖代谢障碍/综述

Key words

Sleep disorders/Diabetes mellitus/Glucose metabolism disorders/Review

分类

医药卫生

引用本文复制引用

李佳琦,严悦蓉,余叶蓉..睡眠障碍与糖尿病的关系及其对糖代谢的影响研究进展[J].中国全科医学,2017,20(11):1300-1304,5.

基金项目

国家自然科学基金资助项目(81600603) (81600603)

中国全科医学

OA北大核心CSTPCD

1007-9572

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