中国实用口腔科杂志2017，Vol.10Issue(3)：171-174,4.DOI:10.19538/j.kq.2017.03.009
实验性1型糖尿病大鼠牙槽骨高度变化研究
The study of alveolar bone height changes in experimental type 1 diabetic rats
摘要
Abstract
Objective To explore the alveolar bone height changes in experimental type 1 diabetic rats.Methods Twelve male Sprague-Dawley (SD) rats were randomly divided into experimental and control groups.The rats in the experimental groups were made type 1 diabetes mellitus (DM) by intraperitoneal injection of streptozotocin (STZ) (60mg/kg),while the control groups were injected with equal volume citrate buffer.All animals were sacrificed after 8 weeks.The alveolar bone loss (ABL) of the first molar,second molar and the third molar were measured from alveolar crest to enamel-cementum junction by stereoscope loupe.Results The rats in the control groups had no obvious bone damage;while experimental groups showed obvious bone destruction horizontally,there was significant difference statistically (P ＜ 0.05).Conclusion The alveolar bone damage was shown in rats with type 1 diabetes mellitus,and was horizontal absorption slowly.关键词
糖尿病/牙槽骨/链脲佐菌素Key words
diabetes mellitus/DM/alveolar/streptozotocin/STZ分类
医药卫生引用本文复制引用
孙尚敏,闫露,潘亚萍,林莉,潘春玲,唐晓琳..实验性1型糖尿病大鼠牙槽骨高度变化研究[J].中国实用口腔科杂志,2017,10(3):171-174,4.基金项目
辽宁省科学技术计划项目(2013225303) （2013225303）
