中国实用口腔科杂志2017，Vol.10Issue(3)：180-185,6.DOI:10.19538/j.kq.2017.03.011
锌对细胞凋亡及纯钛种植体表面骨结合影响研究进展
Research advance of impact of zinc on apoptosis and the osseointegration on the surface of pure titanium implants
摘要
Abstract
Zinc is a necessary trace element for organism,which important to the physiological regulation of organs and tissues.Zinc has an important biological effect in the process of apoptosis;it can inhibit apoptosis and induce apoptosis,both depending on intracellular concentration of zinc.The mechanism of zinc in influencing apoptosis is complex,which is the result of joint action of a variety of factors.Appropriate concentration of zinc coating on the surface of dental implants,which are made of pure titanium,modified by micro-arc oxidation,can promote the proliferation and differentiation of osteoblasts and the formation of bone matrix;also,different concentrations of zinc can affect the apoptosis of osteoblastic cells,probably through a mitochondria-mediated pathway.关键词
锌/细胞凋亡/口腔种植体/成骨细胞Key words
zinc/apoptosis/dental implant/osteoblast分类
医药卫生引用本文复制引用
王品莹,何晶,赵宝红..锌对细胞凋亡及纯钛种植体表面骨结合影响研究进展[J].中国实用口腔科杂志,2017,10(3):180-185,6.基金项目
沈阳市科技计划项目(F11-264-1-25) （F11-264-1-25）
辽宁省科技计划项目(2013225049) （2013225049）
