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肝叶切除与肝门胆管癌根治术联合应用的临床价值研究

张雷 王林 耿智敏 万永 孟凡迪 孟宪魁

中国现代手术学杂志2017,Vol.21Issue(1):5-8,4.
中国现代手术学杂志2017,Vol.21Issue(1):5-8,4.DOI:10.16260/j.cnki.1009-2188.2017.01.002

肝叶切除与肝门胆管癌根治术联合应用的临床价值研究

The Clinical Value of the Hepatic Lobectomy Combined with Radical Resection for Perihilar Cholangiocarcinoma

张雷 1王林 1耿智敏 1万永 1孟凡迪 1孟宪魁1

作者信息

  • 1. 西安交通大学第一附属医院老年外科,陕西西安710061
  • 折叠

摘要

Abstract

Objective To investigate the clinical value of the hepatic lobectomy combined with radical resection of perihilar cholangiocarcinoma.Methods From January 2010 to January 2013,a total of 72 patients with perihilar cholangiocarcinoma in our hospital were analyzed retrospectively.All 72 patients were divided into two groups according to surgical procedure:The control group (n =36) was treated with radical resection of perihilar cholangiocarcinoma,and the observation group (n =36) was treated with hepatic lobectomy combined with radical resection of peri hilar cholangiocarcinoma.The operation result,radical resection rate,postoperative complication rate and 1-,2-,3 year survival rate were compared between two groups.Results The operation time and intra-operative blood loss in the observation group were significantly higher than those in the control group ((305.5 ± 16.7) min vs.(244.3 ± 15.8) min,(341.6 ± 20.7) ml vs.(67.5 ± 4.1) ml,P < 0.05).There was no statistical difference in the hospital stays between two groups (P > 0.05).The radical resection rate of the observation group was 77.8%,and was significantly higher than 27.8% of the control group (P < 0.05).The postoperative complication rate of the observation group was significantly higher than that of the control group (36.1% vs.13.9%,P<0.05).The survival rate of 1-,2-,3 year was 83.3%,50% and 33.3% respectively in the observation group,and was remarkable higher than 52.8%,22.2% and 8.3 % respectively in control group (P < 0.05).Conclusion The surgery of hepatic lobectomy combined with radical resection can play an important role in improving the radical resection rate effectively and increasing the survival rate for perihilar cholangiocarcinoma.

关键词

胆管肿瘤/肝叶切除术/肝门胆管癌根治术

Key words

bile duct neoplasms/hepatic lobectomy/radical resection of perihilar cholangiocarcinoma

分类

医药卫生

引用本文复制引用

张雷,王林,耿智敏,万永,孟凡迪,孟宪魁..肝叶切除与肝门胆管癌根治术联合应用的临床价值研究[J].中国现代手术学杂志,2017,21(1):5-8,4.

中国现代手术学杂志

OACSTPCD

1009-2188

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