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清金固本胶囊质量控制方法研究

李玎 李娜 张敏婕 陈萍

中国药业2017,Vol.26Issue(8):12-16,5.
中国药业2017,Vol.26Issue(8):12-16,5.DOI:10.3969/j.issn.1006-4931.2017.08.004

清金固本胶囊质量控制方法研究

Quality Control of Qingjinguben Capsule

李玎 1李娜 1张敏婕 1陈萍2

作者信息

  • 1. 陕西中医药大学,陕西咸阳 712046
  • 2. 陕西省中医药研究院,陕西西安 710003
  • 折叠

摘要

Abstract

Objective To control the quality of Qingjinguben Capsule. Methods TLC method was used to identify Scutellariae Radix, Platycodonis Radix,Poria,Saposhnikoviae Radix,Codonopsis. The content of baicalin was determined by HPLC. Results The chromato-graphic spots were clear with good separation,the chromatogram for identification by TLC was distinct and highly specific. The linear range was 4. 1-32. 8 μg/ml(r=0. 9999),the average recovery rate was 95. 85%,RSD was 0. 71%(n=6). Conclusion The method can provide reference for the establishment of quality standard of Qingjinguben Capsule.

关键词

清金固本胶囊/薄层色谱鉴别/高效液相色谱法/黄芩苷/含量测定/质量控制

Key words

Qingjinguben Capsule/TLC/HPLC/baicalin/content determination/quality contorl

分类

医药卫生

引用本文复制引用

李玎,李娜,张敏婕,陈萍..清金固本胶囊质量控制方法研究[J].中国药业,2017,26(8):12-16,5.

基金项目

陕西省自然科学基础研究计划项目[ 2012JM4053 ]. ()

中国药业

OACSTPCD

1006-4931

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