中国真菌学杂志2017，Vol.12Issue(2)：102-105,4.
某院念珠菌尿的临床感染特征及其耐药趋势分析
Clinical infection characteristics and analysis of drug resistance trend of candiduria in hospital
曹艳云 1房华 2蔡海斌 1徐顺明1
作者信息
- 1. 上海市浦东新区人民医院皮肤科,上海201299
- 2. 上海市浦东新区人民医院检验科,上海201299
- 折叠
摘要
Abstract
Objective To investigate and analyze the clinical infection characteristics and drug resistance trend of candiduria,to provide evidence for selection of antifungal drugs.Methods Patients who cultured Candida positive in urinary sediment were collected from 2013 to 2016.The strains were identified by CHRO Magar chromogenic medium and the drug susceptibility test was performed with ATB Fungu 3 reagent.Results A total of 202 strains of Candida were isolated,including C.albicans (79.1％),C.tropicalis (10.7％),C.parapsilosis and C.krusei (respectively 5.1％).The Candida were mainly found in emergency department (83 cases),followed by urology (21 cases) and endocrinology (21 cases).Drug sensitivity results showed that Amphotericin B and 5-fluorocytosine had a strong antibacterial activity against Candida.The resistance rate of Candida to fluconazole increased year by year.Candida's resistant to voriconazole and itraconazole was in a fluctuating state,and the resistance rate of Candida was significantly higher in 2016.Conclusion C.albicans was still the most predominant pathogen of candiduria.The drug resistance rates of amphotericin B and 5-fluorocytosine were the lowest,while there was a genus difference in drug resistance of the azoles,and the trends of drug resistance were becoming more serious.关键词
念珠菌/念珠菌尿/耐药性Key words
Candida/candiduria/drug resistance分类
医药卫生引用本文复制引用
曹艳云,房华,蔡海斌,徐顺明..某院念珠菌尿的临床感染特征及其耐药趋势分析[J].中国真菌学杂志,2017,12(2):102-105,4.
