摘要
Abstract
Objective To investigate the clinical features, thrombosis location, treatment and prognosis in patients with intracranial venous sinus thrombosis (CVST) associated with Behcet's disease (BD). Methods We performed a retrospective analysis of clinical data of 9 inpatients with CVST associated with BD in Beijing Tongren hospital of Capital Medical University from January 2014 to August 2016. Results Nine patients (age range 21-47 years, mean age 35.9 years) with CVST associated with BD were collected, of which 2 (22.2%) cases were male. The results of clinical features showed as follows: 1 acute onset (11.1%) and 8 chronic onset (88.9%); 4 headache (44.4%), 1 dizziness (11.1%), 3 paroxysmal amaurosis (33.3%), 5 decreased binocular vision (55.6%), 9 papilledema (100%), 3 diplopia (33.3%) and only 1 tinnitus (11.1%); 7 sigmoid sinus thrombosis (77.8%), 5 transverse sinus thrombosis (55.6%), 1 straight sinus thrombosis (11.1%), 1 inferior sagittal sinus thrombosis (11.1%) and 2 internal jugular vein thrombosis (22.2%); 4 cases involving only 1 sinus (44.4%) and 5 ones involving 2 and more than 2 sinus (55.6%). All patients were given with oral methazolamide 50 mg bid, and glucocorticoids impact treatment for 3 cases (33.3%), of which 1 case (11.1%) combined with warfarin anticoagulant therapy and the other two (22.2%) undergoing lumbar cistern - celiac bypass surgery. After follow-up of 1- 32 months, all patients obviously improved after treatment. Conclusion BD can cause CVST, one or more than one venous sinuses can be involved, and the possibility of BD should be excluded in CVST patients.关键词
白塞病/颅内静脉窦血栓形成Key words
Behcet's disease/Cerebral venous sinus thrombosis
