摘要
Abstract
Objective:To investigate the effect of acupuncture and early rehabilitation training on neurologic function recovery,brain haemodynamics,serum levels of soluble E-selectin (SES) and high sensitive C-reactive protein (hs-CRP) in patients with acute cerebral infartion(ACI).Methods:46 patients with acute cerebral infarction were randomly divided into a rehabilitation group (n =23) and a control group (n =23).Both groups were treated with routine medication.Control group received conventional nursing measures,while on the basis of the therapy in control group,rehabilitation group received acupuncture and early rehabilitation intervention.NIHSS score,Barthel index score and FMA score were compared between two groups.Brain haemodynamics,SES and hs-CRP were detected before treatment and after treatment of four weeks in both groups.Results:Mter treatment of four weeks,NIHSS scores in two groups were lower than those pretreatment (P ＜ 0.01 or 0.05),and the NIHSS score was significantly lower in rehabilitation group than that in control group.BI and FMA scores in both groups were significantly higher than those pretreatment(P ＜ 0.01 or 0.05),and those in rehabilitation group were significantly higher than those in control group(all P ＜ 0.05).After treatment of four weeks,cerebral haemodynamic parameters Qm,Vm in both groups were significantly higher than those pretreatment(P ＜0.01 or 0.05);Qm and Vm in rehabilitation groups were significantly higher than those in control group(all P ＜ 0.05).Rv,DR in both groups were significantly lower than those pretreatment(P ＜ 0.01 or 0.05),and Rv,DR in rehabilitation group were significantly lower than those in control group (all P ＜ 0.05).Mter treatment of four weeks,serum SES and hs-CRP levels in both groups were lower than those pretreatment (P ＜ 0.01 or 0.05).serum SES and hs-CRP levels in rehabilitation group were significantly lower than those in control group(P ＜ 0.01 or 0.05).Conclusion:Acupuncture and early rehabilitation can improve the brain haemodynamics and reduce the levels of serum SES and hs-CRP,promote neurologic function rehabilitation and improve the quality of life in patients with acute cerebral infarction.关键词
急性脑梗死/针灸/早期康复/可溶性E-选择素/高敏C反应蛋白Key words
Acute cerebral infarction/Acupuncture/Early rehabilitation/Soluble E-selectin/High sensitive C-reactive protein分类
医药卫生
