浙江医学2017，Vol.39Issue(5)：332-335,4.DOI:10.12056/j.issn.1006-2785.2017.39.5.2016-1363
原发性周围型微小肺癌临床特征及预后分析
Clinical features and prognosis of primary peripheral lung carcinoma with micro-size
摘要
Abstract
Objective To investigate the clinical characteristics and prognosis of patients with peripheral micro-size lung carcinoma.Methods The clinical features,imaging findings and prognosis of 193 patients with primary peripheral lung carcinoma,whose cancer size was ≤1cm in diameter,were retrospectively analyzed.Results Among 193 patients there were 139 females and 54 males with a mean age of 53.5 ± 10.3 years (22-79).Most of patients had low preoperative peripheral CEA levels (＜5.0IU/ml).Adenocarcinoma was the dominant pathological type (190/193,98.5％),and the main subtypes were adenocarcinoma in situ (AIS) and micro-infiltrating adenocarcinoma (MIA).The CT findings were pure ground glass opacity (pGGO) and mixed ground glass opacity(mGGO).All patients had no lymph node metastasis with a pathological stage 0 or stage I.There were significant differences in gender,smoking status,CEA levels,pathological stages and CT findings among different types of micro-sized lung adenocarcinoma(AIS,MIA,IAC) (all P＜0.05),whereas no significant difference between patients with tumor size 0.5-0.7cm and those 0.7-1.0cm (all P ＞0.05).After 14-96 months follow-up,all patients were alive after surgery.Conclusion The main subtype of micro-sized lung cancer was adenocarcinoma,with no lymph node metastasis and favorable prognosis.Wedge resection and segmentectomy are recommended for those patients with pGGO and normal preoperative CEA level.关键词
微小肺癌/腺癌/肿瘤大小/病理学类型/预后Key words
Micro-sized lung cancer/Adenocarcinoma/Tumor size/Histology/Prognosis引用本文复制引用
柴振达,陈志军,竺王玉,王善军,王兆宇,张永奎..原发性周围型微小肺癌临床特征及预后分析[J].浙江医学,2017,39(5):332-335,4.基金项目
国家卫生计生委科学研究基金(WKJ2014-2-021) （WKJ2014-2-021）
浙江省科技计划项目(2015C33254) （2015C33254）
