浙江医学2017,Vol.39Issue(5):365-366,2.DOI:10.12056/j.issn.1006-2785.2017.39.5.2016-2119
420例流产物染色体核型分析
Cytogenetic analysis of miscarriage samples
摘要
Abstract
Objective To examine the chromosome abnormalities in miscarriage samples.Methods Tissue samples were collected from uterine curettage or vocuum suction in 420 miscarriage patients,and the karyotype analysis was performed.Results There were 145 cases of normal results (34.5%),230 cases of abnormal results (54.8%),and in 45 samples there was no cell growth (10.7%).In 230 abnormal samples numerical abnormalities were the most frequent,including 16-trisomy (42 cases),triploidy (28 cases),monosomy X (25 cases),tetraploidy (12 cases) and 15-trisomy (12 cases);the other abnormalities were chromosome deletion,duplication,insertion and translocation.Conclusion Cytogenetic alterations are important cause of miscarriages and 16-trisomy is the most frequent one.关键词
核型分析/流产物/染色体异常Key words
Karyotype analysis/Miscarriage/Chromosomal alterations引用本文复制引用
邓月月,刘文华,戴莺莺..420例流产物染色体核型分析[J].浙江医学,2017,39(5):365-366,2.