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420例流产物染色体核型分析

邓月月 刘文华 戴莺莺

浙江医学2017,Vol.39Issue(5):365-366,2.
浙江医学2017,Vol.39Issue(5):365-366,2.DOI:10.12056/j.issn.1006-2785.2017.39.5.2016-2119

420例流产物染色体核型分析

Cytogenetic analysis of miscarriage samples

邓月月 1刘文华 1戴莺莺1

作者信息

  • 1. 310008 杭州市妇产科医院妇产科
  • 折叠

摘要

Abstract

Objective To examine the chromosome abnormalities in miscarriage samples.Methods Tissue samples were collected from uterine curettage or vocuum suction in 420 miscarriage patients,and the karyotype analysis was performed.Results There were 145 cases of normal results (34.5%),230 cases of abnormal results (54.8%),and in 45 samples there was no cell growth (10.7%).In 230 abnormal samples numerical abnormalities were the most frequent,including 16-trisomy (42 cases),triploidy (28 cases),monosomy X (25 cases),tetraploidy (12 cases) and 15-trisomy (12 cases);the other abnormalities were chromosome deletion,duplication,insertion and translocation.Conclusion Cytogenetic alterations are important cause of miscarriages and 16-trisomy is the most frequent one.

关键词

核型分析/流产物/染色体异常

Key words

Karyotype analysis/Miscarriage/Chromosomal alterations

引用本文复制引用

邓月月,刘文华,戴莺莺..420例流产物染色体核型分析[J].浙江医学,2017,39(5):365-366,2.

浙江医学

OACSTPCD

1006-2785

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