浙江医学2017，Vol.39Issue(6)：435-437,3.DOI:10.12056/j.issn.1006-2785.2017.39.6.2016-656
纳米炭在胃癌个体化淋巴结清扫术中的应用
Application of nano-carbon particle as trace agent for dissection of metastatic lymph nodes in gastric cancer patients
摘要
Abstract
Objective To investigate the feasibility and clinical effect of the application of nano-carbon particle as a trace agent in radical gastrectomy for gastric cancer.Methods The clinical data of 111 patients with gastric cancer undergoing D2 (D2+) radical gastrectomy with intraoperative injection of nano-carbon particles (study group) and 106 patients undergoing D2 (D2+) radical resection without injection of nano-carbon particles (control group) were retrospectively analyzed.The operation time,intraoperative blood loss,hospitalization time,dissected lymph node number(N1,N2,partial N3 lymph node) and metastatic lymph node number were compared between two groups.Results There was no significant difference in operation time,blood loss and hospitalization time between the two groups (P＜0.05).The number of dissected and metastatic lymph nodes in study group was significantly higher than that of control group,except N1 lymph nodes (P＜0.05).Conclusion The intraoperative application of nano-carbon particle is simple and feasible for guiding the dissection of individual lymph nodes,which can increase the detection rate of lymph node metastasis,and is beneficial to accurate clinical staging and postoperative chemotherapy.关键词
纳米炭/胃肿瘤/淋巴示踪剂/手术Key words
Nano-carbon particle/Stomach neoplasms/Lymphatic tracer/Operation引用本文复制引用
陈柏庆,茅育蕾,章健,张黎,梁军,张涛,裴俊烽,张前进,金冬春,博江河..纳米炭在胃癌个体化淋巴结清扫术中的应用[J].浙江医学,2017,39(6):435-437,3.基金项目
浙江省教育厅科研计划项目(Y201226061) （Y201226061）
绍兴市科技局科研计划项目(2013D10043) （2013D10043）
浙江省医学会临床科研项目(2013ZYC-B) （2013ZYC-B）
浙江省医药卫生技术成果项目(2017ZH024) （2017ZH024）
