肿瘤防治研究2017，Vol.44Issue(4)：253-256,4.DOI:10.3971/j.issn.1000-8578.2017.04.003
鼻咽癌调强放疗中腮腺平均吸收剂量预测模型研究
Prediction Model of Parotid Mean Dose in Intensity Modulated Radiation Therapy on Nasopharyngeal Carcinoma
石翔翔 1唐涛 1陈斌 1庞皓文1
作者信息
- 1. 646000泸州,西南医科大学附属医院肿瘤科
- 折叠
摘要
Abstract
Objective To investigate the prediction model of parotid mean dose and D50％ in intensity modulated radiation therapy(IMRT) on nasopharyngeal carcinoma(NPC).Methods We selected 50 NPC patients who underwent IMRT,scanned the radiotherapy plan CT,analyzed the relationship between the parotid volume and its mean absorbed dose and D50％,and predicted parotid mean dose and D50％ before planning IMRT.Results There were significant correlation between Vparotid/Vparotid and Dmean/ Dprescription(confidence coefficient=0.01,r=0.895),Voverlap/Vparotid and D50％/Dprescription(confidence coefficient=0.01,r=0.812).Matlab software was used to fit the correlation formula.Conclusion For the patients who underwent IMRT,we can predict Dmean and D50％ by Voverlap/Vparotid under the prescription according to the relevant mathematical model fitted in this study before making the radiotherapy plan,and reduce the impact of subjective factors in the radiotherapy plan optimization process,as a standard for assessing programs.关键词
鼻咽癌/调强放疗/腮腺/吸收剂量/预测模型Key words
Nasopharyngeal carcinoma/Intensity modulated radiation therapy/Parotid gland/Absorbed dose/Prediction model分类
医药卫生引用本文复制引用
石翔翔,唐涛,陈斌,庞皓文..鼻咽癌调强放疗中腮腺平均吸收剂量预测模型研究[J].肿瘤防治研究,2017,44(4):253-256,4.
