摘要
Abstract
Objective:To understand the types of bacteria and drug sensitivity in bronchoalveoar lavage fluid (BALF) of children with lower respiratory tract infection,and to provide basis for clinical rational drug use.Methods:The BALF of three hundreds and sixty eight children who treated with fiber bronchoscope were collected in 2012 to 2014.The identification and drug susceptibility testing for bacteria were performed using MicroScan WalkAway 40 analyzer from America and DL analyzer from China.Results:Two hundreds and thirteen strains of pathogenic bacteria were isolated.Among them,gram-negative bacilli accounted for 92.5％,gram-positive bacilli accounted for 4.7％,Candida albicans accounted for 2.8％.The main types of these bacteria were Klebsiella pneumoniae,Pseudomons aeruginosa,Acinetobacter baumannii,Escherichia coli.The results of drug susceptibility testing showed that the drug resistance of Acinetobacter baumannii to 12 kinds of antibiotis was generally low,the drug resistance rates to every tested antibiotis was less than 30％.The drug resistance rates of Pseudomonas aeruginosa to ticarcillin/clavulanic acid,piperacillin/tazobactam,ceftazidime,imipenem,amikacin,ciprofloxacin,levofloxacin were less than 20％.The drug resistance rates of Klebsiella pneumoniae and Escherichia coli to imipenem were 0,and to other tested antimicrobial agents showed varying degrees of resistance.Conclusion:The main pathogenic bacteria isolated from bronchoalveoar lavage fluid are gram-negative bacilli,the drug resistance of bacteria to different antibacterial drug are different,and reasonable use of antiotics is the key of infection controlling.关键词
支气管肺泡灌洗液/病原菌/耐药性/儿童Key words
bronchoalveoar lavage fluid/pathogenic bacteria/drug resistance/child分类
医药卫生
