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帕金森病多模态MRI研究进展

王凤丽 许亮

国际医学放射学杂志2017,Vol.40Issue(3):268-272,5.
国际医学放射学杂志2017,Vol.40Issue(3):268-272,5.DOI:10.19300/j.2017.Z4435

帕金森病多模态MRI研究进展

Research progress of multimodality MRI in Parkinson's disease

王凤丽 1许亮2

作者信息

  • 1. 南开大学医学院, 天津 300071
  • 2. 天津市人民医院影像学部
  • 折叠

摘要

Abstract

Parkinson's Disease(PD) is the second most common neurodegenerative disease after Alzheimer's disease. Its pathological change is death of dopaminergic neurons in the substantianigra, consenquently the dopamine level of the striatumis decreased, resulting in a series of clinical symptoms.The regional brain change has been intensivily investigated with structural MRI.With the development of multimodality MRI,researchers can further evaluate PD from the hemodynamic, cerebral white matter fiber tracts imaging, metabolism level and functional connectivity.Moreover, multimodality MRI can offer radiological evidences for clinical diagnosis, treatment, and prognosis.We reviewed the research progress of multimodality MRI in PD.

关键词

帕金森病/结构磁共振成像/功能磁共振成像/多模态

Key words

Parkinson's disease/Structural magnetic resonance imaging/Functional magnetic resonance imaging/Multimodality

分类

医药卫生

引用本文复制引用

王凤丽,许亮..帕金森病多模态MRI研究进展[J].国际医学放射学杂志,2017,40(3):268-272,5.

国际医学放射学杂志

OA北大核心CSTPCD

1674-1897

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