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山牡荆提取物对大鼠慢性肾炎模型的药效学实验研究

王飞娟 景鹏 王燕 张爽 高洁

中医药导报2017,Vol.23Issue(8):28-30,37,4.
中医药导报2017,Vol.23Issue(8):28-30,37,4.

山牡荆提取物对大鼠慢性肾炎模型的药效学实验研究

The Pharmacodynamic Study of Extract of Vitex Quinata on Rat Model of Chronic Glomerulonephritis

王飞娟 1景鹏 2王燕 1张爽 1高洁1

作者信息

  • 1. 陕西国际商贸学院医药学院,陕西咸阳712046
  • 2. 咸阳市中心医院,陕西咸阳712000
  • 折叠

摘要

Abstract

Objective:To investigate the therapeutic effect of extract of Vitex quinata on rat model of chronic glomerulonephritis.Methods:The 60 rats were randomly divided into four groups,referred to as mountain vitex extract treatment group,positive control group,model group and normal control group,each 15 rats.Forward three groups rat model of chronic glomerulonephritis,given the appropriate medication at a dose of 10 mg/kg/d,for 4 weeks.Results:The corresponding index,urine protein,serum creatinine,blood urea nitrogen,serum lipid levels of rat model significantly improved with extract of Vitex quinata.Conclusion:Extract of Vitex quinata has a therapeutic effect in rats with chronic nephritis.

关键词

山牡荆提取物/大鼠/慢性肾炎

Key words

extract of Vitex quinata/rats/chronic glomerulonephritis

分类

医药卫生

引用本文复制引用

王飞娟,景鹏,王燕,张爽,高洁..山牡荆提取物对大鼠慢性肾炎模型的药效学实验研究[J].中医药导报,2017,23(8):28-30,37,4.

基金项目

陕西国际商贸学院科学研究项目(编号:SMXY201404) (编号:SMXY201404)

陕西省大学生创新创业训练计划项目 ()

中医药导报

OACSTPCD

1672-951X

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