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代谢组学在中药毒性及其作用机制中的应用

杨代晓 杨建云 肖炳坤 黄荣清

中医药导报2017,Vol.23Issue(8):76-79,4.
中医药导报2017,Vol.23Issue(8):76-79,4.

代谢组学在中药毒性及其作用机制中的应用

The Application of Metabonomics in the Traditional Chinese Medicine Toxicity and Its Mechanism of Action

杨代晓 1杨建云 2肖炳坤 2黄荣清2

作者信息

  • 1. 江西中医药大学,江西 南昌 330004
  • 2. 军事医学科学院放射与辐射医学研究所,北京100850
  • 折叠

摘要

Abstract

In recent years metabonomics based on its unique advantages is applied in pharmaceutical,biology and medicine and other fields,metabonomics can reflect the biological characteristics from the overall level,determine the mechanisms of drug action,it is conducive to the development of the modernization of traditional Chinese medicine.This article through to the metabolites omics various induction,system analysis of the development of metabonomics,through the analysis of metabonomics toxicity and mechanism of the traditional Chinese medicine research,summarized the application of metabonomics in traditional Chinese medicine research value;provided a basis for the application of metabonomics.

关键词

代谢组学/中药毒性/作用机制/应用价值

Key words

metabonomics/traditional Chinese medicine toxicity/mechanism of action/application value

分类

医药卫生

引用本文复制引用

杨代晓,杨建云,肖炳坤,黄荣清..代谢组学在中药毒性及其作用机制中的应用[J].中医药导报,2017,23(8):76-79,4.

基金项目

国家自然科学基金项目(No.21375147) (No.21375147)

十二五国家科技重大专项“重大新药创制”综合性新药研究开发技术大平台(No.2012ZX09301003-001-010) (No.2012ZX09301003-001-010)

国家“重大新药创制”科技重大专项(2011ZXJ0910101B) (2011ZXJ0910101B)

中医药导报

OACSTPCD

1672-951X

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