解放军医学杂志2017,Vol.42Issue(4):347-353,7.DOI:10.11855/j.issn.0577-7402.2017.04.14
自身免疫性脑炎治疗进展
Recent advances in the treatment of autoimmune encephalitis
摘要
Abstract
Autoimmune encephalitis is a kind of inflammatory disease of central nervous system caused by abnormal immune response of body immune system to neuronal antigen,and is generally considered to be reversible encephalitis caused by noninfectious factors.Its characteristic manifestations include acute and subacute onset of cognitive dysfunction,epilepsy and mental disorder.With the discovery of related antibodies,summaries of clinical syndrome and application of new functional imaging instruments,the diagnosis of autoimmune encephalitis is increasingly standardized.The priority treatment of autoimmune encephalitis is immunomodulatory therapy,including glucocorticoid,immunoglobulin,plasma exchange and immunosuppressant.The other treatments could be the related tumor resection,electroshock therapy,etc.The symptoms in most patients can get substantial relief with active treatment.The present paper would focus on the research progress in treatment of autoimmune encephalitis.关键词
自身免疫性脑炎/免疫调节药物/治疗Key words
autoimmune encephalitis/immunomodulatory drugs/treatment分类
医药卫生引用本文复制引用
邵龙,王威,郑娜,蒋胶胶,张家堂..自身免疫性脑炎治疗进展[J].解放军医学杂志,2017,42(4):347-353,7.基金项目
全军医学科技“十二五”科研项目(CWS11J064)This work was supported by the "Twelfth Five-Year" Medical Science and Technique Foundation of PLA (CWS11J064) (CWS11J064)