实用临床医药杂志2017，Vol.21Issue(7)：5-7,3.DOI:10.7619/jcmp.201707002
早期应用西酞普兰对急性皮质脑梗死患者运动功能恢复的影响
Influence of early application of citalopram on motor function recovery of patients with acute cortical cerebral infarction
摘要
Abstract
Objective To explore the influence of citalopram on early recovery of motor function in patients with acute cortical infarction.Methods A total of 276 patients with acute cerebral infarction were randomly divided into observation group and control group,138 cases in each group.Patients in control group were treated with anti-platelet,blood lipid,protective nerve and rehabilitation therapy.The observation group was given citalopram hydrobromide tablets on the basis of control group.Results The incidence rate of depression in the observation group was 18.1％,which was significantly lower than 42.7％ in the control group (P ＜ 0.05).After treatment,HDRS score and NIHSS score in the observation group were significantly lower than the control group (P ＜ 0.05).In the observation group,after treatment of 30 days and 90 days,the increasing scores of hand motor function of FMA were 4.1 ± 1.0 points and 6.5 ± 2.5 points,which were significantly higher than 1.4 ± 0.7 points and 2.5 ± 1.5 points (P ＜ 0.05).After treatment of 30 days,the BI score of observation group was significantly higher than control group (P ＜ 0.05).Conclusion Early application of citalopram can effectively reduce the incidence rate of post-stroke depression in patients with acute cerebral infarction,promote the recovery of motor function and improve the quality of prognosis.关键词
急性皮质脑梗死/抑郁/西肽普兰/运动功能Key words
acute cortical infarction/depression/citalopram/motor function分类
医药卫生引用本文复制引用
肖静,黄园媛,江思德,邹耀兵,鄢宗仁,唐明山..早期应用西酞普兰对急性皮质脑梗死患者运动功能恢复的影响[J].实用临床医药杂志,2017,21(7):5-7,3.基金项目
重庆市科技计划项目(科技2015016) （科技2015016）
