临床小儿外科杂志2017，Vol.16Issue(2)：138-141,150,5.DOI:10.3969/j.issn.1671-6353.2017.02.008
胆道闭锁肝移植术后早期肝动脉血栓的诊断及处理
Diagnosis and treatment of early-stage hepatic artery thrombosis after liver transplantation for biliary atresia
摘要
Abstract
Objective To evaluate the diagnosis and treatment of early-stage hepatic artery thrombosis (HAT) after liver transplantation (LT) for biliary atresia (BA) in children.Methods A total of 41 BA children undergoing LT between June 2006 and April 2014 were analyzed retrospectively.During early post-LT period,the relevant serum biochemical parameters were detected.And hepatic arterial blood flow was monitored by color Doppler ultrasound.Hepatic artery angiography or laparotomy was performed on recipients with suspected HAT.Results The incidence of HAT was 21.95％ (9/41 transplants).Interventional therapy,emergency hepatic artery revascularization and re-transplantation were effective rescue measures.Among 9 cases of postoperative HAT,the mortality causes included HAT (n =2),severe lung infection of Klebsiella pneumoniae (n =2),hindgut drain septic shock (n =1),severe capillary leak syndrome (n =1) and primary hepatic failure after re-transplantation (n =1).Conclusions In BA children,LT has a higher incidence of HAT and HAT is an important factor of decreased survival rate during early postoperative stage.Hepatic arteriography and thrombolysis or laparotomy and thrombectomy are effective in the diagnosis and treatment of hepatic artery thrombosis.关键词
胆道闭锁/肝移植/肝动脉血栓/手术后并发症/儿童Key words
Biliary Atresia/Liver Transplantaion/Hepatic Artery Thrombosis/Postoperative Complications/Child引用本文复制引用
韩环立,张明满,郭春宝,康权,李英存,蒲从伦..胆道闭锁肝移植术后早期肝动脉血栓的诊断及处理[J].临床小儿外科杂志,2017,16(2):138-141,150,5.基金项目
国家临床重点专科建设项目资助(编号[2013]544) （编号[2013]544）
