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HP感染与胃癌发生部位、分类及分期分析

贺正希 李斌 黄进 裴海平 周建华

中南医学科学杂志2017,Vol.45Issue(3):276-279,4.
中南医学科学杂志2017,Vol.45Issue(3):276-279,4.DOI:10.15972/j.cnki.43-1509/r.2017.03.015

HP感染与胃癌发生部位、分类及分期分析

Relationship between Helicobacter pylori and histologicalsubtype,location of gastric cancer

贺正希 1李斌 1黄进 1裴海平 2周建华3

作者信息

  • 1. 中南大学 湘雅医院肿瘤科, 湖南 长沙 410008
  • 2. 中南大学湘雅医院 普外科
  • 3. 中南大学湘雅医院病理科
  • 折叠

摘要

Abstract

Objective In recent years,studies have confirmed that Helicobacter pylori (HP) infection is involved in the development of gastric cancer (GC).This study analyzed the relationship between HP infection and the location and classification of gastric cancer and staging.Methods Retrospective analysis of 183 cases of gastric cancer patients implemented radical gastrectomy,Gastric cancer samples were classified according to Lauren and Lauren.Pathological sections were stained with HE and Giemsa to observe HP infection.Results Of the 183 cases of gastric malignancy,168 cases (91.8%) of gastric adenocarcinoma,11 cases (6%) of lymphoma,2 cases (1.0%) of leiomyosarcoma,1 case of gastrointestinal stromal tumor (GIST) % And Kaposi's sarcoma in 1 case (0.5%).168 cases of GC patients,the average age of 67 years,60% of men.55.4% occurred in the gastric antrum,21.4% occurred in the gastric body,14.3% in the stomach (P=0.018);gastrointestinal cancer accounted for 65%,diffuse type gastric cancer accounted for 24.8%,mixed 10.2%;69.6% were infected by HP (64% intestine,33% diffuse,10% mixed,P=0.327).Conclusion There is a difference in HP infection rate between gastric antrum cancer,gastric cancer and gastric cancer group,suggesting that HP infection may be related to the occurrence of gastric cancer.

关键词

胃癌(GC)/幽门螺杆菌(HP)/组织学类型/肿瘤位置

Key words

gastric cancer/helicobacter pylori/histological subtype/tumor location

分类

医药卫生

引用本文复制引用

贺正希,李斌,黄进,裴海平,周建华..HP感染与胃癌发生部位、分类及分期分析[J].中南医学科学杂志,2017,45(3):276-279,4.

中南医学科学杂志

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2095-1116

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