新医学2017，Vol.48Issue(5)：351-353,3.DOI:10.3969/j.issn.0253-9802.2017.05.014
新生儿红细胞增多症38例临床分析
Clinical analysis of 38 cases of neonatal polycythemia
摘要
Abstract
Objective To summarize the clinical characteristics and experience in the diagnosis and treatment of the neonatal polycythemia (NP). Methods Clinical data including clinical manifestations, treatment, prognosis and follow-up of 38 NP cases were retrospectively analyzed. Results Among 38 NP cases, 10 were preterm infants, 27 full-term infants and 1 perinatal infant. Eight infants were aged < gestational age, 27 at gestational age and 3 > gestational age. Thirty-three cases were single birth and 5 twin pregnancy birth. Four cases had umbilical cord entanglement. Two cases were complicated with asphyxia upon birth delivery. Two presented with meconium-stained amniotic fluid. Nine cases had a medical history of transplacental transfusion diseases including twin pregnancy transfusion, fetomaternal transfusion and perinatal hypoxia, etc. Twelve cases had no history of specific diseases. Six mothers were diagnosed with gestational diabetes mellitus, 2 with gestational hypertension and 1 with hypothyroidism. Primary symptoms included hyperbilirubinemia (73.7%), cyanosis, reduction in blood oxygen or shortness of breath (60.5%) and sanguineous appearance (21.1%), etc. Twenty-nine cases received partial exchange transfusion including plasma transfusion in 3, albumin transfusion in 6 and physiological saline in 20. Intravenous infusion of low-molecular-weight dextran was administered in 16 cases. Corresponding measures were actively taken to treat relevant complications. Two cases were discharged without treatment. For the remaining 36 cases, hemoglobin level and hematocrit were significantly decreased, relevant symptoms were obviously improved and physical signs restored to normal after corresponding interventions. Conclusions NP is associated with chronic intrauterine hypoxia, fetal blood transfusion and other factors. Partial exchange transfusion is an efficacious and safe approach for the treatment of NP. A majority of affected infants obtain favorable clinical prognosis.关键词
新生儿/红细胞增多症/部分换血Key words
Neonate/Polycythemia/Partial exchange transfusion引用本文复制引用
钟晓冰,朱顺叶,唐本玉..新生儿红细胞增多症38例临床分析[J].新医学,2017,48(5):351-353,3.基金项目
广东省科技计划项目(2014A020212392) （2014A020212392）
