中国临床药理学与治疗学2017，Vol.22Issue(3)：316-320,5.
疏肝柴胡散对胆囊切除术后综合征的临床疗效及安全性
Clinical efficacy and safety of chaihu shugan powder in the treatment of post-cholecystectomy syndrome
摘要
Abstract
AIM:To evaluate the clinical efficacy and safety of chaihu shugan powder combined with danshu capsule and xiaoyan lidan tablet in the treatment of post-cholecystectomy syndrome.METHODS:Ninety patients with post-cholecystectomy syndrome were divided into control group (45 cases) and treatment group (45 cases) according to random number table method.The control group was given danshu capsule,2 capsules/time,3 times/d,and xiaoyan lidan tablet,6 pills/time,3 times/d,and the control group was given chaihu shugan powder,1 dose/d,on the basis of control group.After one month therapy,the clinical efficacy,clinical symptoms such as abdominal pain,abdominal distention,anepithymia,nausea and adverse reactions were observed in two groups,and self-rating anxiety scale (SAS) and self-rating depression scale (SDS) were used to evaluate the patient's bad mood.RESULTS:The total effective rate 97.78％ (44/45) in treatment group was higher than that of the control group 77.78％ (35/45) (P ＜0.05).The scores of abdominal pain (0.94 ± 0.52),abdominal distension (0.86 ± 0.45),anepithymia (0.73 ± 0.47) and nausea(0.72 ±0.41)in treatment group were significantly lower than the control group (2.62 ± 0.51),(1.71 ±0.43),(1.51 ±0.52) and(1.41 ±0.45) (P ＜ 0.05).The scores of SAS (42.64 ± 7.35) and SDS(32.37 ± 7.09) in treatment group were significantly lower than the control group (50.31 ± 8.62) and (48.41 ±7.11)(P＜0.05).No obvious adverse reactions were found in two groups.CONCLUSION:Chaihu shugan powder combined with danshu capsule and xiaoyan lidan tablet in the treatment of post-cholecystectomy syndrome have better clinical curative effect,can improve clinical symptoms,increase patients' enthusiasm and bad no adverse reactions.It was worthy of clinical popularization and application.关键词
胆囊切除术后综合征/疏肝柴胡散/胆舒胶囊/消炎利胆片/不良情绪/安全性Key words
post-cholecystectomy syndrome/chaihu shugan powder/danshu capsule/xiaoyan lidan tablet/bad mood/safety分类
医药卫生引用本文复制引用
魏锋,王大禹,魏云海..疏肝柴胡散对胆囊切除术后综合征的临床疗效及安全性[J].中国临床药理学与治疗学,2017,22(3):316-320,5.基金项目
浙江省医药卫生科技计划项目(2014ZHB007) （2014ZHB007）
