中国全科医学2017，Vol.20Issue(13)：1587-1591,5.DOI:10.3969/j.issn.1007-9572.2017.13.012
肠型胃癌和弥漫型胃癌的临床特点及预后研究
Clinical Characteristics and Prognosis of Intestinal-type and Diffuse-type Gastric Cancer
摘要
Abstract
Objective To discuss clinical characteristics and prognosis of intestinal-type and diffuse-type gastric cancer.Methods A total of 392 patients with gastric cancer receiving operative treatment in the surgical ward of Heping Hospital Affiliated to Changzhi Medical College from January 1st 2007 to December 30th 2015 were selected.Among them,231 (58.9%) were intestinal type and 161 (41.1%) were diffuse type.The epidemiological questionnaire gastric cancer was established.The trained professionals according to unified standards collected the information of patients with gastric cancer.Their basic situation (gender,age,height,body mass,educational level,marital status,blood type,helicobacter pylori infection,family history of cancer);lifestyle and habits (smoking,drinking,eating speed,eating hot food,eating Chinese sauerkraut/pickles/preserved vegetables,eating fried foods);and pathological diagnosis and clinical staging were included in the collected information.The telephone follow-up of patients was made to inquire about survival by people having master degree or above in central lab of the hospital,and would be conducted until December 30th 2015.Results There were no significant differences in gender,body mass index (BMI),educational level,marital status,blood type,helicobacter pylori infection and history of cancer between patients with intestinal-type cancer and patients with diffuse-type gastric cancer (P>0.05).There were significant differences in age between patients with intestinal-type cancer and patients with diffuse-type gastric cancer (P<0.05).There were significant differences in smoking and drinking between patients with intestinal-type cancer and patients with diffuse-type gastric cancer (P<0.05).There were no significant differences in eating speed,eating hot food,eating Chinese sauerkraut/pickles/preserved vegetables,eating fried foods between patients with intestinal-type cancer and patients with diffuse-type gastric cancer (P>0.05).There was no significant difference in T phase and M phase between patients with intestinal-type cancer and patients with diffuse-type gastric cancer (P>0.05).There was significant difference in N phase between patients with intestinal-type cancer and patients with diffuse-type gastric cancer (P<0.05).Three hundred and forty patients with gastric cancer had completed the followed up,the follow-up rate was 86.7%.By the end of follow-up,the survival rate of patients with intestinal-type gastric cancer was 66.5% (129/194),the median survival time was 24 months;and the survival rate was 52.7% (77/146) in patients with diffuse-type gastric cancer,and the median survival time was 18 months.The survival curves between patients with intestinal-type gastric cancer and patients with diffuse-type gastric cancer were significantly different (P<0.05).Conclusion The clinical manifestations and prognosis of Lauren classification were different.Lauren classification plays a decision-making role in the treatment and prevention of gastric cancer.关键词
胃肿瘤/Lauren分型/临床特点/预后Key words
Stomach neoplasms/Lauren classification/Clinical characteristics/Prognosis分类
医药卫生引用本文复制引用
曹文君,李敏,李慧娟..肠型胃癌和弥漫型胃癌的临床特点及预后研究[J].中国全科医学,2017,20(13):1587-1591,5.基金项目
山西省基础研究计划项目(2015021185) （2015021185）
国家自然科学基金资助项目(81302518) （81302518）
山西省长治医学院创新团队(CX201403) （CX201403）
