中国全科医学2017，Vol.20Issue(15)：1809-1812,4.DOI:10.3969/j.issn.1007-9572.2017.15.005
无症状性颈动脉狭窄与认知功能障碍关系的研究进展
Advances in the Study of Asymptomatic Carotid Artery Stenosis and Cognitive Impairment
摘要
Abstract
Carotid artery stenosis is one of the risk factors for ischemic stroke.With symptoms such as cerebral and retinal ischemia,it is called symptomatic carotid artery stenosis,without these features,it is referred to as asymptomatic carotid artery stenosis.Asymptomatic carotid artery stenosis has no clinical symptoms,but it is associated with cognitive decline which may eventually result in dementia.Therefore,asymptomatic carotid artery stenosis should not be underestimated.In this paper,the recent progress in the study of asymptomatic carotid artery stenosis and cognitive impairment is summarized.The results show that asymptomatic carotid artery stenosis is an independent risk factor for cognitive decline,it can lead to cognitive impairment by destroying the brain connectivity network,damaging white matter and gray matter microstructure,reducing the cerebral perfusion and interfering with the electrophysiological activity of the cerebral cortex.Therefore,carrying out early clinical intervention,such as carotid endarterectomy(CEA) and carotid artery stenting(CAS),is of great significance for the prevention and treatment of cognitive impairment in patients with asymptomatic carotid artery stenosis.关键词
颈动脉狭窄/认知障碍/颈动脉内膜切除术/颈动脉支架术Key words
Carotid stenosis/Cognition disorders/Endarterectomy/carotid/Carotid artery stenting分类
医药卫生引用本文复制引用
李小旋,任艳艳,安金,董艳红,吕佩源..无症状性颈动脉狭窄与认知功能障碍关系的研究进展[J].中国全科医学,2017,20(15):1809-1812,4.基金项目
河北省科技计划项目(142777870,16397795D) （142777870,16397795D）
2013年省级重大医学科研课题(zd2013005) （zd2013005）
