中国畜牧兽医2017，Vol.44Issue(4)：994-1000,7.DOI:10.16431/j.cnki.1671-7236.2017.04.008
光周期对于绒山羊毛囊干细胞激活的影响
Effects of Photoperiod on Stem Cells Activation in Cashmere Goat Hair Follicles
摘要
Abstract
In order to extend the anagen of cashmere goat hair follicles and increase the production of cashmere,this study was performed with artificially shorten the daylight time among Arbas White cashmere goats.Skin tissue sections from cashmere goats were collected to compare the morphologic changes between artificial daylight and natural daylight,and immunohistochemical method was used to study the hair follicle cell proliferation and important protein expression in related signaling pathways.The results showed that strong cell proliferation occurred in cashmere goat hair follicle cells during artificial daylight,plenty of cytokeratin 15 (K15) positive signals were distributed in the outer root sheath,β-catenin protein was actively expressed in hair matrix and root sheath, indicating that the hair follicles were in the anagen growth phase;Meanwhile,cashmere goat hair follicles under natural daylight were in telogen with weak signals.Above all prove that short photoperiod played an important role in promoting hair follicle growth,the artificial short photoperiod could change hair follicle growth cycle and make hair follicles earlier enter to the anagen growth phase,causing a variety of typical gene expressions during hair follicle growth.关键词
绒山羊/短日照/细胞增殖/干细胞/生长调控Key words
cashmere goat/short photoperiod/cell proliferation/stem cells/growth regulation分类
农业科技引用本文复制引用
刘斌,郭俊,勿都巴拉,马跃军,辛雷勇,赵存发,李玉荣,尹俊..光周期对于绒山羊毛囊干细胞激活的影响[J].中国畜牧兽医,2017,44(4):994-1000,7.基金项目
国家自然科学基金项目(31260545) （31260545）
国家公益性行业(农业)科研专项(201303059) （农业）
内蒙古自治区自然科学基金项目(2014BS0333) （2014BS0333）
内蒙古自治区创新基金项目(2013CXJJM03) （2013CXJJM03）
内蒙古农牧业科学院青年创新基金项目(2013QNJJM05) （2013QNJJM05）
内蒙古自然科学基金重大项目(2013ZD06) （2013ZD06）
