中国中医药信息杂志2017，Vol.24Issue(6)：13-16,4.DOI:10.3969/j.issn.1005-5304.2017.06.004
基于多元统计的非酒精性脂肪性肝病中医病机研究
Study on TCM Pathogenesis of Nonalcoholic Fatty Liver Disease Based on Multivariate Statistical Analysis
摘要
Abstract
Objective To explore the TCM pathogenesis regularity of nonalcoholic fatty liver disease (NAFLD);To provide basis for clinical syndrome differentiation and treatment. Methods A cross-sectional study was used. The clinical observation form of NAFLD was used to collect the patient data. Factor analysis and singular value decomposition methods were used to study the internal factors of the four diagnostic characteristics. The differences between the various analytical methods were compared. Results Factor analysis used the α factor analysis method, the principal component method, and the image factor method. The results of α-factor analysis were the best. The first three factors had the highest explanatory rates of data, namely spleen-dampness factor, kidney deficiency factor and qi deficiency factor, which constituted the basic pathogenesis factor of NAFLD. The singular value decomposition method obtained 3 singular values, namely spleen and kidney qi deficiency, liver and kidney yin deficiency, and qi and yin deficiency, also highlighted the spleen and kidney deficiency in the pathogenesis of NAFLD. Conclusion Spleen-kidney deficiency plays an important role in the pathogenesis of NAFLD. Treatment based on deficiency for nonalcoholic fatty liver disease has great clinical significance.关键词
非酒精性脂肪性肝病/病机/因子分析/奇异值分解Key words
nonalcoholic fatty liver disease/pathogenesis/factor analysis/singular value decomposition分类
医药卫生引用本文复制引用
刘宏,王景泉,马菁蔓,林文志,张国丽..基于多元统计的非酒精性脂肪性肝病中医病机研究[J].中国中医药信息杂志,2017,24(6):13-16,4.基金项目
北京市丰台区卫生系统科研项目(2012-39) （2012-39）
