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Long-term Levodopa Treatment Accelerates the Circadian Rhythm Dysfunction in a 6-hydroxydopamine Rat Model of Parkinson's Disease

Si-Yue Li Ya-Li Wang Wen-Wen Liu Dong-Jun Lyu Fen Wang Cheng-Jie Mao Ya-Ping Yang Li-Fang Hu Chun-Feng Liu

中华医学杂志(英文版)2017,Vol.130Issue(9):1085-1092,8.
中华医学杂志(英文版)2017,Vol.130Issue(9):1085-1092,8.DOI:10.4103/0366-6999.204920

Long-term Levodopa Treatment Accelerates the Circadian Rhythm Dysfunction in a 6-hydroxydopamine Rat Model of Parkinson's Disease

Long-term Levodopa Treatment Accelerates the Circadian Rhythm Dysfunction in a 6-hydroxydopamine Rat Model of Parkinson's Disease

Si-Yue Li 1Ya-Li Wang 2Wen-Wen Liu 2Dong-Jun Lyu 1Fen Wang 2Cheng-Jie Mao 2Ya-Ping Yang 1Li-Fang Hu 1Chun-Feng Liu2

作者信息

  • 1. Department of Neurology and Suzhou Clinical Research Center of Neurological Disease, The Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu 215004, China
  • 2. Institute of Neuroscience, Soochow University, Suzhou, Jiangsu 215123, China
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摘要

关键词

Circadian Rhythm/Levodopa/Oxidopamine/Parkinson Disease

Key words

Circadian Rhythm/Levodopa/Oxidopamine/Parkinson Disease

引用本文复制引用

Si-Yue Li,Ya-Li Wang,Wen-Wen Liu,Dong-Jun Lyu,Fen Wang,Cheng-Jie Mao,Ya-Ping Yang,Li-Fang Hu,Chun-Feng Liu..Long-term Levodopa Treatment Accelerates the Circadian Rhythm Dysfunction in a 6-hydroxydopamine Rat Model of Parkinson's Disease[J].中华医学杂志(英文版),2017,130(9):1085-1092,8.

基金项目

This work was supported by grants from the National Natural Science Foundation of China (No.91649114),Jiangsu Provincial Special Program of Medical Science (No.BL2014042),the Plans for Graduate Research and Innovation in Colleges and Universities of Jiangsu Province (No.KYZZ15_0334),and Suzhou Clinical Research Center of Neurological Disease (No.Szzx201503). (No.91649114)

中华医学杂志(英文版)

OACSCDCSTPCDMEDLINESCI

0366-6999

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