摘要
Abstract
Objective:To observe and analyze the influence of tirofiban on the serum cardiac troponin T (cTnT) level and short term prognosis in patients with acute non ST segment elevation myocardial infarction(NSTEMI).Methods: 116 patients with NSTEMI were selected as the research subjects,and randomly divided into the observation group and the control group.The patients in the control group were treated with oral aspirin and clopidogrel combined with subcutaneous injection of low molecular weight heparin,while the patients in the observation group were treated with intravenous thrombolysis of tirofiban on the basis of the therapy of the control group.The incidence of the major adverse cardiac events (MACE) during 60 d of the patients in the two groups were observed and compared.The serum cTnT levels on admission,12 h of the treatment,24 h of the treatment of the patients in the two groups were detected and compared.Results: The overall incidence of MACE of the patients in the observation group during the follow-up period was significantly lower than that in the control group,the difference was statistically significant (P<0.05).At the time points of 12 h of the treatment and 24 h of the treatment,the serum cTnT levels of the patients in the observation group were significantly lower than those in the control group,the differences were statistically significant (P<0.05).Conclusion: In the treatment of patients with NSTEMI,the application of combination with intravenous thrombolysis of tirofiban can improve the short-term prognosis of patients,reduce the myocardial damage in patients and has better clinical curative effects.关键词
替罗非班/急性/非ST段抬高心肌梗死/肌钙蛋白TKey words
Tirofiban/Acute/Non ST segment elevation myocardial infarction/Cardiac troponin T分类
医药卫生
