磁共振成像2017,Vol.8Issue(5):343-348,6.DOI:10.12015/issn.1674-8034.2017.05.005
肝脏原发性神经内分泌肿瘤的MRI表现及其病理学基础分析
MRI findings of primary hepatic neuroendocrine tumors:correlation with pathology
刘军 1罗佳文 2边杰 2康永琨 2陶娟 2白婷婷2
作者信息
- 1. 大连市中心医院放射科,大连116033
- 2. 大连医科大学附属第二医院放射科,大连 116027
- 折叠
摘要
Abstract
Objective: To investigate MR imaging findings of primary hepatic neuroendocrine tumors (PHNETs) and their correlation with the 2010 WHO pathological classification. Materials and Methods: We analyzed MRI imagings of 6 patients who were diagnosed with PHNET and correlated the data with the 2010 WHO classification of neuroendocrine tumors. Results: According to the 2010 WHO classification system, 1 case was defined as G1, 3 cases were defined as G2, and 2 cases were defined as G3. The Grade 1 tumor was singular, solid nodules with prolonged enhancement from the arterial phase to the delayed phase. The lesion showed hypointensity on T1-weighted imaging, mildy high intensity on T2-weighted and homogeneous. The tumor cell arranged in a beam, and blood sinus was abundant. Grade 2 tumors could have a singular or multiple distribution pattern, signal intensities were heterogeneous on T1-and T2-weighted imaging with hemorrhage and necrosis. The tumor showed marked peripheral enhancement in the arterial phase and slight hyper-intensity relatived to the surrounding liver parenchyma in the delayed phase. Grade 3 tumors had multiple lesions, internal necrosis or coagulation necrosis, which showed the slight and prolonged enhancement from the arterial phase to the delayed phase. HE staining of the tumor showed tumor cell arranged as solid nests, and blood sinus was mildly abundant. Conclusions: MRI can reflect pathological features of PHNETs, which are helpful in accurately diagnosing PHNETs.关键词
神经内分泌瘤/肝肿瘤/磁共振成像/病理学Key words
Neuroendocrine tumors/Liver neoplasms/Magnetic resonance imaging/Pathology分类
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刘军,罗佳文,边杰,康永琨,陶娟,白婷婷..肝脏原发性神经内分泌肿瘤的MRI表现及其病理学基础分析[J].磁共振成像,2017,8(5):343-348,6.