重庆医学2017，Vol.46Issue(14)：1927-1930,4.DOI:10.3969/j.issn.1671-8348.2017.14.019
3例子宫体原发性非霍奇金淋巴瘤的临床病理观察
The clinical and pathological diagnosis of three cases of uterine corpus primary NHL
余燕青 1熊一峰 1梅金红1
作者信息
- 1. 南昌大学第一附属医院病理科,江西南昌 330000
- 折叠
摘要
Abstract
Objective To discuss pathological features of three cases of uterine primary NHL(non Hodgkin′s lymphoma).Methods The clinical and pathological data of 3 cases of NHL were collected.Immunohistochemical method was used to label the tumor cells.Their histological types were classified by the latest WHO Classification of Tumors of Haematopoietic and Lymphoid Tissues,and then differential diagnosis with other uterus diseases was offered.Results Three cases were presented with abnormal vaginal bleeding or ejecting as the first symptom,which was easily misdiagnosed as common diseases of the uterus in preliminary clinical and pathological diagnosis.Histopathology of general uterus specimens demonstrated that case one expressed CD3,CD56,TiA-1 and so on,and detected EBV virus cells expression,which supported the diagnosis of NK/T cell lymphoma.Another two cases expressed B cell-specific markers(CD20) and so on,and these tumor cells volume was 3 times larger than that of lymphocyte.These tumor cells had high proliferation index and supported diffuse large B-cell lymphoma diagnosis.Conclusion The tumor cells are like lymphocytes.We infiltrate endometria and myometrium,which is difficult to identify from endometria stromal sarcoma and other tumors,and need to use immunohistochemistry(IHC) for definitive diagnosis and differential diagnosis.关键词
淋巴瘤,非霍奇金/子宫肌层/子宫内膜/子宫肿瘤/病例报告/免疫组织化学Key words
lymphoma/non-Hodgkin/myometrium/endometrium/uterine neoplasms/case reports/immunohistochemistry分类
医药卫生引用本文复制引用
余燕青,熊一峰,梅金红..3例子宫体原发性非霍奇金淋巴瘤的临床病理观察[J].重庆医学,2017,46(14):1927-1930,4.
