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母胎界面维生素D受体表达与复发性自然流产相关及可能的机制

闫春芳 闫晓婷 惠凌云 王丽 白娥 于学文

中国妇幼健康研究2017,Vol.28Issue(5):519-521,3.
中国妇幼健康研究2017,Vol.28Issue(5):519-521,3.DOI:10.3969/j.issn.1673-5293.2017.00.010

母胎界面维生素D受体表达与复发性自然流产相关及可能的机制

Relationship between vitamin D receptor expression on fetal-maternal interface and recurrent miscarriage and possible mechanism

闫春芳 1闫晓婷 2惠凌云 2王丽 2白娥 2于学文2

作者信息

  • 1. 西安市第四医院生殖中心,陕西 西安710004
  • 2. 西安交通大学第一附属医院,陕西 西安710061
  • 折叠

摘要

Abstract

Objective To explore the relationship between vitamin D receptor (VDR) expression on fetal-maternal interface and recurrent miscarriage (RM) and placental hormone.Methods Villous and decidual tissue samples from patients with RM and those at normal early pregnancy were collected outpatient department of obstetrics and gynecology in the First Affiliated Hospital of Xi'an Jiaotong University from July to September in 2014.VDR, human chorionic gonadotropin receptor (HCGR), estrogen receptor (ER) and progesterone receptor (PR) mRNA levels in two groups were detected by fluorescence real-time quantitative polymerase chain reaction (FQ-PCR) and expression difference was compared

关键词

复发性自然流产/维生素D受体/母胎界面/绒毛膜促性腺激素受体/雌激素受体

Key words

recurrent miscarriage (RM)/vitamin D receptor (VDR)/fetal-maternal interface/human chorionic gonadotropin receptor (HCGR)/estrogen receptor (ER)

分类

医药卫生

引用本文复制引用

闫春芳,闫晓婷,惠凌云,王丽,白娥,于学文..母胎界面维生素D受体表达与复发性自然流产相关及可能的机制[J].中国妇幼健康研究,2017,28(5):519-521,3.

基金项目

国家自然科学基金资助项目(81270697) (81270697)

中国妇幼健康研究

1673-5293

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