中国妇幼健康研究2017,Vol.28Issue(5):600-602,3.DOI:10.3969/j.issn.1673-5293.2017.05.038
新生儿B族链球菌败血症15例的临床分析
Clinical analysis of 15 cases of neonatal group B streptococcal septicemia
刘婉文 1利汉其1
作者信息
- 1. 广东省佛山市南海区人民医院儿科,广东 佛山 528200
- 折叠
摘要
Abstract
Objective To investigate clinical features of neonatal group B streptococcal (GBS) septicemia.Methods Fifteen GBS septicemia newborns with positive blood cultures of GBS treated in Nanhai District People's Hospital of Foshan in Guangdong from January 2012 to December 2015 were selected, and their clinical features were analyzed.Results In 15 cases of GBS septicemia, 10 were early onset and 5 were late onset GBS sepsis.Respiratory symptoms were major symptoms of cases with early onset GBS sepsis, which attacked within 24 hours after birth.First symptom of neonates with late onset GBS sepsis was high fever, and all cases were infected with purulent meningitis.Level of white blood cells in neonates with GBS septicemia was low, reaction of procalcitonin was sensitive, and reaction of C reactive protein was relatively lagged.GBS strains were highly sensitive to penicillin and vancomycin, and sensitivity of both was 100%, followed by sensitivity of cefuroxime (93.33%).Conclusion Onset of neonatal GBS sepsis is dangerous, and can cause permanent neurological damage.Prenatal GBS screening conducted by hospital has great value in reducing neonatal GBS infection.Early treatment should be given to neonates with white blood cell decrease, abnormal PCT and respiratory symptoms.关键词
新生儿/B族链球菌/败血症/临床分析Key words
neonate/group B streptococcus (GBS)/septicemia/clinical analysis分类
医药卫生引用本文复制引用
刘婉文,利汉其..新生儿B族链球菌败血症15例的临床分析[J].中国妇幼健康研究,2017,28(5):600-602,3.