郑州大学学报（医学版）2017，Vol.52Issue(3)：274-281,8.DOI:10.13705/j.issn.1671-6825.2017.03.009
新疆哈萨克族15个常染色体STR位点检测及40个中国人群遗传关系
Analysis of 15 autosomal STR among Xinjiang Kazaks and the inference of genetic relationship among 40 Chinese populations based on the 15 STRs
摘要
Abstract
Aim: To investigate the population genetic data of Xinjiang Kazaks and to analyze the genetic distance and genetic relationship among 40 Chinese populations including Kazaks.Methods: The 15 autosomal STR loci in Xinjiang Kazaks samples were analyzed;corresponding frequency data of 15 STR loci of other Chinese populations was collected from published literatures.The genetic distance(Rst) among the 40 populations was calculated by Phylip 3.69 and Arlequin 3.5, and the phylogenetic tree was constructed with Neighbor-Joining method.Results: All the other 14 STRs except TPOX had high He and PIC values more than 0.7 in Xinjiang Kazaks.The mean Rst among the 40 populations was 0.055 1, the mean Rst was 0.044 9 among the 18 Han populations, and the mean Rst was 0.057 6 among the other 22 minorities.In the tree graph, the Han nationality displayed a lot of branches, showing a trend of more and more diversity;some of the minorities gathered together although they were geographically distant.Conclusion: The 15 autosomal STR are highly polymorphic in Xinjiang Kazaks and the 15 STR frequency data published by the forensic science community can be conveniently used for the study of human evolution, ethnic origin and ethnic group relationships.关键词
法医学/常染色体/STR/遗传距离/中国人群Key words
forensic medicine/autosome/STR/genetic distance/Chinese population分类
社会科学引用本文复制引用
王文菲,吕自力,张勇,钟明霞,贾馨怡,曾昭书..新疆哈萨克族15个常染色体STR位点检测及40个中国人群遗传关系[J].郑州大学学报（医学版）,2017,52(3):274-281,8.基金项目
国家自然科学基金资助项目 31071100 （）
河南省教育厅高等学校重点科研项目 15A180021 （）
