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妊娠合并癫痫患者的临床特征及处理对策

白琳 张潇 路文革 代允义 许晓峰

中国实用神经疾病杂志2017,Vol.20Issue(9):34-36,3.
中国实用神经疾病杂志2017,Vol.20Issue(9):34-36,3.

妊娠合并癫痫患者的临床特征及处理对策

Clinical characteristics and treatments of epilepsy during pregnancy

白琳 1张潇 1路文革 2代允义 2许晓峰1

作者信息

  • 1. 河南商丘市第一人民医院妇产科 商丘 476000
  • 2. 河南商丘市第一人民医院神经内科 商丘 476000
  • 折叠

摘要

Abstract

Objective To investigate clinical characteristics and treatments of epilepsy during pregnancy.Methods We retrospectively analyzed the clinical data of 62 pregnant women with epilepsy who were in obstetrical department from February 2010 to December 2015.Results Of the 62 selected cases,there were 21 cases with symptomatic epilepsy,36 with cryptogenic epilepsy and 5 with idiopathic epilepsy.In addition,5 patients stopped the antiepileptic drugs(AEDs)before pregnancy and 42 patients regularly continued the AEDs among whom 24 patients were treated with monotherapy,18 patients were treated with multi-drug medication and 15 patients did not adhered to AEDs.Seizures during pregnancy increased in 17 patients(27.4%),reduced in 19 patients(30.7%)and remained unchanged in 26 patients(41.9%).33 patients(53.2%)received natural childbirth,while 29 patients(46.8%)received cesarean section.There were 3 infants of neonatal asphyxia,4 infants of low-birth weight,and one infant of neonatal malformation.Conclusion Complications in both mothers and neonates can be reduced and pregnancy outcome can be improved by carrying out consultation and evaluation before pregnancy,standardizing treatment of AEDs,enhancing the number of obstetric examination during pregnancy and strengthening multidisciplinary cooperative management.

关键词

癫痫/妊娠/抗癫痫药物/新生儿畸形

Key words

Epilepsy/Pregnancy/Antiepileptic drugs/Neonatal malformations

分类

医药卫生

引用本文复制引用

白琳,张潇,路文革,代允义,许晓峰..妊娠合并癫痫患者的临床特征及处理对策[J].中国实用神经疾病杂志,2017,20(9):34-36,3.

中国实用神经疾病杂志

1673-5110

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