中国实用神经疾病杂志2017，Vol.20Issue(10)：9-12,4.
胼胝体和扣带回弥散张量成像改变对皮质下缺血性血管性痴呆患者认知功能障碍的影响
Effectof MR diffusion tensor imaging in subcortical ischemic vascular dementia with cognitive impairment on corpus callousm and cingulate bundles
摘要
Abstract
Objective To investigate the abnormality of association fiber tracts in corpus callousm and cingulate bundles using diffusion tensor imaging (DTI) to detect the relationship between the DTI parameters and cognitive status in subcortical ischemic vascular dementia (SIVD).Methods A region of interest-based DTI approach was applied to explore fiber tract differences and neuropsychological assessments between 60 SIVD patients and 40 matched nondemented normal aging.Results Compared with control group,SIVD had significant lower FA and greater ADC in the genu of corpus callosum,bilateral cingulate bundles,while the splenium of corpus callosum had no significant difference.Significant positively correlation was found between MMSE and the FA value of bilateral cingulate bundles and the genu of corpus callosum.Conclusion The changes of DTI parameters in corpus callousm and cingulate bundles may predict the cognitive impairment of SIVD.关键词
皮质下缺血性血管性痴呆/弥散张量成像/胼胝体/扣带回Key words
Subcortical ischemic vascular dementia/Diffusion tensor imaging/Corpus callousm/Cingulate bundles分类
医药卫生引用本文复制引用
周树虎,梁汝庆,申雪花..胼胝体和扣带回弥散张量成像改变对皮质下缺血性血管性痴呆患者认知功能障碍的影响[J].中国实用神经疾病杂志,2017,20(10):9-12,4.基金项目
济宁市科技发展项目(2014jnyyf04) （2014jnyyf04）
