摘要
Abstract
Objective To investigate the related risk factors for deep venous thrombosis (DVT) in critically neurological patients with cerebral infarction,and to evaluate the efficacy of low molecular weight heparin (LMWH) and intermittent pneumatic compression (IPC) on preventing DVT.Methods We retrospectively analyzed the clinical data of 270 critically neurological patients with cerebral infarction.Both single factor analysis and multivariate logistic regression analysis were used to the independent risk factors.We counted morbidity rate of DVT observed by color Doppler ultrasound (CDUS) after the treatment of LMWH and IPC.Results Single factor analysis indicated that bedridden time,duration of mechanical ventilation,age,hypertension,diabetes mellitus,NIHSS scores,venepuncture position,stimulant drugs,TC,TG,HDL-C,LDL-C,fibrinogen,PT and D-Dimer were high risk factors for DVT (all P<0.05),and anticoagulant and anti-platelet drugs are protective factors (all P<0.05),while gender,smoking showed no significant differences (P>0.05).In multivariate Logistic regression analysis,age,NIHSS scores,D-Dimer and fibrinogen were independent risk factors for DVT and anticoagulant and anti-platelet drugs were protective factors.LMWH combined with IPC was the best strategy for preventing DVT (P<0.05).Conclusion The critically neurological patients with cerebral infarction have high morbidity rate of DVT and have many risk factors for DVT.The incidence of DVT reduces by using LMWH and IPC in cerebral infarction patients.关键词
脑梗死/危险因素/深静脉血栓形成/低分子肝素/间歇性气压治疗Key words
Cerebral infarction/Risk factors/Deep venous thrombosis/Low molecular weight heparin/Intermittent pneumatic compression分类
医药卫生
