中国实用神经疾病杂志2017，Vol.20Issue(10)：23-26,4.
结核性脑膜炎临床特点脑脊液及影像学表现的相关研究
Research on clinical features,MRI manifestations and changes of cerebrospinal fluid of tubercular meningitis
摘要
Abstract
Objective To explore clinical features,MRI manifestations and changes of cerebrospinal fluid (CSF) of tubercular meningitis(TBM).Methods We summarized the clinical features,MRI characteristics and dynamic indicators of CSF of 75 cases with TBM treated in our hospital from October 2011 to October 2015.Results Thirty percent of the included cases presented cough,expectoration,shortness of breath and other ex-brain tuberculosis symptoms as initial-visit symptoms,except for fever,headache,emesis and other complains.79% cases were misdiagnosed as virus meningitis.After anti-tuberculosis medications,chloride level at first recovered,followed by protein,glucose and ADA levels,and intracranial pressure and cell population renewed most slowly.In addition,both brain parenchyma and meninges were affected in TBM patients.Brain MRI scan showed positive rate of 80% and enhancement scan showed positive rate of 96.9%.Conclusion Tubercular meningitis which is a multi-organ disease may be easily misdiagnosed as virus meningitis.It is necessary to actively seek ex-brain tuberculosis locations.MRI may early find out characteristic focus with high positive rate.More and more simple and noninvasive modern technology should be applied to look for acid-fast bacilli of CSF,providing etiological evidences for diagnosis.关键词
结核性脑膜炎/早期诊断/磁共振表现/脑脊液Key words
Tubercular meningitis/Early diagnosis/MRI features/CSF分类
医药卫生引用本文复制引用
李军霞,陈颜强,赵青,何红彦,孟艺哲..结核性脑膜炎临床特点脑脊液及影像学表现的相关研究[J].中国实用神经疾病杂志,2017,20(10):23-26,4.基金项目
2016年度河北省卫计委医学科学研究重点课题计划,编号:20160491 （）
