中国实用神经疾病杂志2017，Vol.20Issue(10)：26-29,4.
客家人群颈动脉闭塞的临床特点及相关危险因素分析
Analysis of clinical characteristics and risk factors for carotid artery occlusion in Hakka population
摘要
Abstract
Objective To analyze the clinical characteristics and risk factors of carotid artery occlusion in Hakka population.Methods Totally 120 cases with carotid artery occlusion admitted to our hospital and another 120 cases without carotid artery occlusion were selected as study subjects,whose outcomes of CT angiography (CTA) of cervical arteries,brain MRI and brain MRA and the levels of triglyceride (TG),total cholesterol (TC),low-density lipoprotein cholesterol (LDL-C),high-density lipoprotein cholesterol (HDL-C),blood glucose (Glu),homocysteine (Hcy),C-reactive protein (CRP) and glycosylated hemoglobin (HbA1c) and other related blood biochemical indexes were retrospectively analyzed in order to investigate the clinical characteristics and related risk factors of carotid artery occlusion in Hakka people.Results Of the 120 cases with carotid artery occlusion,93 cases (77.5%) presented anterior circulation ischemia,8 cases (6.67%) presented posterior circulation ischemia and 19 cases (15.83%) had no symptoms,which showed no statistical differences (P>0.05).Among 120 cases,there were 89 cases with the opening of posterior communication artery and 45 cases with the opening of anterior communication artery,which showed statistically significant difference (P<0.05).There were statistical differences in gender,age,the levels of TG,LDL-C,HDL-C,CRP,HbA1c and Hcy and the histories of coronary heart disease,hypertension and diabetes mellitus between patients with carotid artery occlusion and patients without carotid artery occlusion (P<0.05).In addition,the levels of Hcy,HbA1c and LDL-C,diabetes,hypertension and coronary heart disease were responsible for the related risk factors for carotid artery occlusion.Conclusion Firstly,carotid artery occlusion in Hakka population mainly presents the manifestations of anterior circulation ischemia including hemiplegia,aphasia,hemidysesthesia,headache and transient monocular blindness.Secondly,a few clinical manifestations of posterior circulation ischemia contain recurrent dizziness or sudden syncope.Thirdly,posterior communication artery may be the crucial compensation approach.Last but not least,the levels of Hcy,HaA1c and LDL-C,diabetes,hypertension and coronary heart disease which are risk factors of carotid artery occlusion,play important roles in carotid artery occlusion.关键词
客家人群/颈动脉闭塞/临床特点/危险因素/Logistic回归分析Key words
Hakka population/Carotid artery occlusion/Clinical characteristics/Risk factors/Logistic regression analysis分类
医药卫生引用本文复制引用
周坤元,李水彬,成钢卫,凌维汉,赖舒帆,涂加善,朱钦辉,钟锐..客家人群颈动脉闭塞的临床特点及相关危险因素分析[J].中国实用神经疾病杂志,2017,20(10):26-29,4.基金项目
梅州市科技计划项目(201613032) （201613032）
