中国实用神经疾病杂志2017，Vol.20Issue(11)：15-18,4.
12例可逆性后部白质脑病综合征的临床特点
Clinical features of 12 patients with reversible posterior leukoencephalopathy syndrome
摘要
Abstract
Objective To analyze the clinical features of reversible posterior leukoencephalopathy syndrome(RPLS).Methods Clinical data including the clinical presentation,laboratory finding and imaging features of twelve patients diagnosed of RPLS by People's Hospital of Henan Province from June 2015 to September 2016 were analyzed.Results Eleven cases of female and one case of male were identified.Ten cases presented with eclampsia,seven of which combined a low level blood platelet.Seizure(10/12),headache(7/12)and visual disturbance(6/12)were observed.Radiological imaging showed symmetrical lesions in posterior brain matter,low density on brain CT and vasogenic edema on MRI,with fronto-parietal lobe,basal ganglia region,callosum,cerebellum involved accasionally.Reexamination after treatment showed completely remission in four cases.Elevated level of LDH was detected in 11/12 cases,7 of which accompanied by reduced platelet level,elevated white blood cell and creatine kinase(CK).Conclusion RPLS is a central nervous system disease featured by headache,seizure,blurred vision and consciousness disturbance.Brain MRI shows vasogenic edema.Lower level of platelet is a possible cause of the disease.Positive treatment is correlated with a better prognosis.关键词
可逆性后部白质脑病综合征/血管源性水肿/临床特点Key words
Reversible posterior leukoencephalopathy syndrome/Vasogenic edema/Clinical features分类
医药卫生引用本文复制引用
仝莹,袁丽品,张钱林,张元杏..12例可逆性后部白质脑病综合征的临床特点[J].中国实用神经疾病杂志,2017,20(11):15-18,4.基金项目
河南省科技厅科技攻关项目(编号122102310160) （编号122102310160）
